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BioWorld - Wednesday, April 22, 2026
Home » Authors » Brian Orelli

Brian Orelli

Articles

ARTICLES

Despite availability of equity capital, royalty deals abound

April 13, 2015
By Brian Orelli
In spite of increased biotech valuations providing for access to capital through the equity markets, the market for capital from the sale of royalties and structured debt tied to product sales is as hot as it's ever been.
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VCs start 2015 off with a bang, IPOs more like a whimper

April 2, 2015
By Brian Orelli
Neither snow in Boston nor a drought in California could stop venture capitalists from handing out cash in the first quarter to start-ups and established private companies alike.
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Cystic fibrosis firms highlight precision medicine's potential

March 30, 2015
By Brian Orelli
With different mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) causing different severities of the disease and requiring different drugs to increase protein function, cystic fibrosis (CF) is the poster child of precision medicine.
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The other March Madness: Data from ACC (the heart one)

March 23, 2015
By Brian Orelli
Like the basketball Atlantic Coast Conference, the other ACC, the American College of Cardiology, ramps up this time of year with its annual scientific session.
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New spin on thin: CVOT and orphan data, ANDAs filed

March 16, 2015
By Brian Orelli
In drug development, it can be difficult to follow the crowd. And that goes double for a market like obesity that's struggled to gain traction.
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Hot capital markets push pharma to early stage deals

March 2, 2015
By Brian Orelli
SAN DIEGO – The capital flowing in the public markets makes it easier for biotechs to gain funding through IPOs and secondary offerings. Companies raised $6.5 billion through IPOs last year and more established public companies were able to add nearly $16.7 billion to their coffers according to BioWorld Snapshots.
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Hepatitis C market in flux: new data, discounts & lost BTDs

Feb. 17, 2015
By Brian Orelli
The hepatitis C market seems to do things in pairs.
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Biotechs welcome spotlight on precision medicine

Feb. 9, 2015
By Brian Orelli
As part of his proposed budget, President Barack Obama recommended spending $215 million on a Precision Medicine Initiative. (See BioWorld Today, Feb. 2, 2015.)
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Obesity market gets more players; improving, but challenges remain

Feb. 2, 2015
By Brian Orelli
The approval of Takeda Pharmaceuticals U.S.A.'s and Orexigen Therapeutics Inc.'s Contrave (naltrexone and bupropion) in September and Saxenda (liraglutide) from Novo Nordisk A/S last month doubled the number of obesity drugs approved by the FDA in the last two and a half years.
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Melanoma just the beginning for PD-1 pathway drugs

Jan. 20, 2015
By Brian Orelli
Both Merck & Co. Inc.’s Keytruda (pembrolizumab) and Bristol-Myers Squibb Co.’s Opdivo (nivolumab) were approved by the FDA to treat advanced metastatic melanoma last year, but that’s only the start of the possibilities for the PD-1 pathway drugs. (See BioWorld Today, Sept. 5, 2014.)
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