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BioWorld - Thursday, December 25, 2025
Home » Authors » Tamra Sami

Articles by Tamra Sami

T cells attacking cancer cells

Lepu out-licenses T-cell engagers to newco Excalipoint for $857M

Aug. 5, 2025
By Tamra Sami
No Comments
Lepu Biopharma Co. Ltd. has out-licensed two preclinical T-cell engagers to Shanghai-based newco Excalipoint in a deal worth $857.5 million plus equity interest. Under the deal terms, Excalipoint gains an exclusive global license to CTM-012 and CTM-013, developed by Lepu’s Topabody T-cell engager platform. In exchange, Lepu will receive $10 million up front and up to $847.5 million in development and commercial-based milestones, plus tiered royalties on sales.
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HKEX on phone, digital stock chart

Chinese vaccine maker Ab&B Bio announces $66M Hong Kong IPO

Aug. 5, 2025
By Tamra Sami
No Comments
Chinese vaccine company Ab&B Bio-tech announced an IPO listing on the Hong Kong Stock Exchange (HKEX:2627) under which it hopes to raise up to HK$518.36 million (US$66 million) to commercialize its influenza and human rabies vaccines in China and internationally.
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Neurology illustration

Alterity develops novel MRI biomarker to track disease progression in MSA

Aug. 5, 2025
By Tamra Sami
No Comments
Alterity Therapeutics Ltd. helped develop a new neuroimaging biomarker called the multiple system atrophy index (MSA-AI), which looks to be a more reliable biomarker for tracking disease progression of MSA.
Read More
Colorized scanning electron micrograph of a T cell

Australian researchers identify world-first treatments to prevent HTLV-1 infection

Aug. 5, 2025
By Tamra Sami
No Comments
Around 10 million people globally live with the life-threatening human T-cell lymphotropic virus type-1 (HTLV-1), yet it remains a poorly understood disease that currently has no preventative treatments and no cure.
Read More
T cells attacking cancer cells

Lepu out-licenses T-cell engagers to newco Excalipoint for $857M

Aug. 4, 2025
By Tamra Sami
No Comments
Lepu Biopharma Co. Ltd. has out-licensed two preclinical T-cell engagers to Shanghai-based newco Excalipoint in a deal worth $857.5 million plus equity interest. Under the deal terms, Excalipoint gains an exclusive global license to CTM-012 and CTM-013, developed by Lepu’s Topabody T-cell engager platform. In exchange, Lepu will receive $10 million up front and up to $847.5 million in development and commercial-based milestones, plus tiered royalties on sales.
Read More
HKEX on phone, digital stock chart

Chinese vaccine maker Ab&B Bio announces $66M Hong Kong IPO

Aug. 1, 2025
By Tamra Sami
No Comments
Chinese vaccine company Ab&B Bio-tech announced an IPO listing on the Hong Kong Stock Exchange (HKEX:2627) under which it hopes to raise up to HK$518.36 million (US$66 million) to commercialize its influenza and human rabies vaccines in China and internationally.
Read More
Neurology illustration

Alterity develops novel MRI biomarker to track disease progression in MSA

July 31, 2025
By Tamra Sami
No Comments
Alterity Therapeutics Ltd. helped develop a new neuroimaging biomarker called the multiple system atrophy index (MSA-AI), which looks to be a more reliable biomarker for tracking disease progression of MSA. Developed using deep learning methods, the MSA-AI offers a superior, objective and quantifiable measure of brain atrophy in MSA patients.
Read More
Colorized scanning electron micrograph of a T cell

Australian researchers identify world-first treatments to prevent HTLV-1 infection

July 31, 2025
By Tamra Sami
No Comments
Around 10 million people globally live with the life-threatening human T-cell lymphotropic virus type-1 (HTLV-1), yet it remains a poorly understood disease that currently has no preventative treatments and no cure. That could soon change after Australian researchers discovered that existing HIV drugs can suppress transmission of the HTLV-1 virus in mice.
Read More
Colorized scanning electron micrograph of a T cell
Infection

Australian researchers identify world-first treatments to prevent HTLV-1 infection

July 30, 2025
By Tamra Sami
No Comments
Around 10 million people globally live with the life-threatening human T-cell lymphotropic virus type-1 (HTLV-1), yet it remains a poorly understood disease that currently has no preventative treatments and no cure. That could soon change after Australian researchers discovered that existing HIV drugs can suppress transmission of the HTLV-1 virus in mice.
Read More

GSK, Hengrui in $12.5B deal for HRS-9821 and 11 other drugs

July 29, 2025
By Tamra Sami
No Comments
Hengrui Pharmaceuticals Co. Ltd. is out-licensing to GSK plc its potential best-in-class phase I phosphodiesterase 3 and 4 inhibitor (HRS-9821) for treating chronic obstructive pulmonary disease along with 11 additional programs in development for $500 million up front and up to $12 billion in potential milestones.
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