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BioWorld - Wednesday, April 8, 2026
Home » Keywords » DDR inhibitors

Items Tagged with 'DDR inhibitors'

ARTICLES

Concept art for damaged DNA structure
Cancer

Rakovina makes progress on ATR inhibitor program

July 23, 2025
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Rakovina Therapeutics Inc. has reported progress in its AI-driven KT-5000AI program, advancing the development of precision ATR (ataxia telangiectasia and Rad3-related) inhibitors designed to disrupt the DNA damage response (DDR) pathway in cancer cells. Through its collaboration with Variational AI Inc., Rakovina has evaluated a vast chemical space of potential molecular structures using Variational’s AI Enki platform to identify novel compounds
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Ribbons of digital data
Cancer

Rakovina advances ATR inhibitors into preclinical testing

March 13, 2025
Rakovina Therapeutics Inc. has received the first synthesized batch of AI-generated ATR inhibitor compounds developed in collaboration with Variational AI Inc. The companies partnered last year to leverage the Enki generative AI platform for the development of next-generation DNA damage response (DDR) inhibitors.
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Group photo, including Onconic CEO John Kim, at Kosdaq

Cancer, GI-focused Onconic shares take off after ₩20B IPO

Dec. 24, 2024
By Marian (YoonJee) Chu
Onconic Therapeutics Inc., a subsidiary of Jeil Pharmaceutical Co. Ltd., saw its shares (KOSDAQ:476060) ascend for two consecutive days after debuting with a ₩20.15 billion (US$13.89 million) IPO on the Korea Exchange Dec. 19. Seoul, South Korea-based Onconic’s Kosdaq IPO offered about 1.55 million shares at ₩13,000 each, which was lowered from its original price band of ₩16,000 to ₩18,000 per share after demand forecasting.
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Group photo, including Onconic CEO John Kim, at Kosdaq

Cancer, GI-focused Onconic shares take off after ₩20B IPO

Dec. 20, 2024
By Marian (YoonJee) Chu
Onconic Therapeutics Inc., a subsidiary of Jeil Pharmaceutical Co. Ltd., saw its shares (KOSDAQ:476060) ascend for two consecutive days after debuting with a ₩20.15 billion (US$13.89 million) IPO on the Korea Exchange Dec. 19. Seoul, South Korea-based Onconic’s Kosdaq IPO offered about 1.55 million shares at ₩13,000 each, which was lowered from its original price band of ₩16,000 to ₩18,000 per share after demand forecasting.
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Illustration of DNA double helix, DNA damage with TCGA letters flying around
Cancer

Rakovina, Variational AI to target DNA damage response

Sep. 18, 2024
Rakovina Therapeutics Inc. and Variational AI Inc. have entered into a research collaboration to identify and develop novel small-molecule therapies against DNA damage response (DDR) targets for the treatment of cancer.
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Respiratory

Chiesi Farmaceutici divulges new DDR inhibitors for fibrosis

May 15, 2023
Chiesi Farmaceutici SpA has synthesized pyrrolidine derivatives acting as discoidin domain-containing receptor DDR1 and DDR2 inhibitors reported to be useful for the treatment of fibrosis and idiopathic pulmonary fibrosis (IPF).
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