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Home » Newsletters » BioWorld

BioWorld

Jan. 19, 2018

View Archived Issues

In the clinic

GC Pharma Corp., formerly Green Cross Corp., of Yongin, South Korea, plans to start enrollment in a phase II/III trial testing GC-1102 (hepabig-gene) to prevent the recurrence of hepatitis B virus infection following liver transplantation in early 2018. Read More

Other news to note

The Cell and Gene Therapy (CGT) Catapult, of London, announced a partnership with London-based Freeline Therapeutics Ltd., a company focused on the development of adeno-associated virus-based gene therapies, to further develop the company's manufacturing platform at the CGT Catapult's large-scale GMP manufacturing center in Stevenage, Hertfordshire, U.K. Read More

Financings

GPB Capital Holdings LLC, of New York, made a debt investment in Torrance, Calif.-based Emmaus Life Sciences Inc. consisting of a $30 million senior secured convertible note with warrants, with $20 million in proceeds delivered up front. Read More

Circle Pharma's work with Pfizer yields new macrocyclic peptides

Circle Pharma Inc., of South San Francisco, said its first collaboration with Pfizer Inc. has led to the identification of a series of bioavailable macrocyclic peptides capable of acting as potent and cell-permeable modulators of CXCR7. Read More

FDA releases spate of drug and device guidances

If the FDA is aiming to break records for producing guidances this year, it's off to a good start. Read More

Better preclinical models, iterative research needed in drug discovery: U.K. report

LONDON – Drug discovery in the U.K. needs to be radically reshaped, ditching "irrelevant" animal models in favor of more testing on human tissues and cells, according to a new report by the Medicines Discovery Catapult (MDC). Read More

Beigene advances combo PD-1 strategy with Mirati deal; launches $750M offering

SHANGHAI – Beigene Ltd. nabbed the Asia-Pacific rights to sitravatinib from Mirati Therapeutics Inc. in a $10 million cash deal, valued at $123 million when additional milestones roll in. The Beijing-based firm also just announced a $750 million public offering to support its growing immuno-oncology pipeline. Read More

Pandion pads coffers with $58M series A to fund bispecifics platform, pipeline

With more than two decades of experience in immunology and inflammatory diseases, Anthony Coyle was hankering for the opportunity to shift the treatment paradigm from systemic immunosuppressives, which temper disease but come with long-term consequences to patients, to "a different type of approach" that would modulate the immune system. Read More

Regulatory front

The U.S. Trade Representative (USTR) called out two online marketplaces for facilitating global trade of counterfeit and illegal drugs. Read More

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