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Home » Newsletters » BioWorld

BioWorld

April 1, 2020

View Archived Issues
Lung cancer illustration

Another COVID-19 casualty: Ose shutters phase III Tedopi trial in NSCLC despite positive interim analysis

DUBLIN – Ose Immunotherapeutics SA finds itself in the difficult place of hitting the primary endpoint of the first part of a phase III trial of Tedopi, a therapeutic vaccine, in non-small-cell lung cancer (NSCLC) while having to terminate the study without completing the crucial second part. Read More
Coronavirus-lungs-test-tube

Just breathe: Ethris, Neurimmune developing inhaled mRNA-encoded COVID-19 antibodies

DUBLIN – Ethris GmbH and Neurimmune AG have formed a collaboration to develop nebulized, mRNA-encoded monoclonal antibodies directed at SARS-CoV-2, which will be delivered directly to the lungs of patients with COVID-19. Read More
Hydroxychloroquine

Desperation drives shortage of antimalarial drugs used to treat COVID-19

The jury is still out on how much hydroxychloroquine and chloroquine actually help in the treatment or prevention of COVID-19, but desperate times have led desperate health care providers to use the antimalarial drugs to treat patients in desperate need of coronavirus cures. Read More

Iteos draws $125M in second series B close to advance I-O pipeline

LONDON – Immuno-oncology specialist Iteos Therapeutics Inc. raised $125 million in the second tranche of its series B, bringing the total for the round to $175 million and fueling clinical development of a pipeline of drugs targeting PD-1 resistance. Read More
Dollar-arrow-up.png

An $80M series B propels Pandion’s progress in the clinic

Kendall Square was a great jumping-off point for Cambridge, Mass.’s Pandion Therapeutics Inc. but with an $80 million series B in its pocket, the time has come to pick up sticks to accommodate its growth. Read More

Nucleotide’s in: Gene therapy high water lifts Affinia with $60M series A

The allure of gene therapy was proved yet again as Waltham, Mass.-based Affinia Therapeutics Inc. bagged an oversubscribed $60 million series A financing to boost the push for drugs to benefit people affected by muscle and central nervous system conditions. Read More

FDA accepts Mesoblast’s BLA for pediatric GVHD stem cell therapy under priority review

PERTH, Australia –Australian stem cell therapy company Mesoblast Ltd. announced that the FDA has accepted its BLA for priority review for its allogeneic mesenchymal precursor cell therapy, remestemcel-L, for children with acute steroid-refractory graft-vs.-host disease (aGVHD). Read More

Appointments and advancements for April 1, 2020

New hires and promotions in the biopharma industry, including: Brainstorm, Harpoon, Locana, Plus, Rockwell, Sutura. Read More

Financings for April 1, 2020

Biopharmas raising money in public or private financings, including: Aclaris, Aspen Neuroscience, Bellerophon, Keros, Phio, Therapix, Vivus. Read More

In the clinic for April 1, 2020

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Alligator, Eusa, Horizon, Inflarx, Inmed, Lidds, Novo Nordisk, Oncoceutics, Orchard, Ose, Theranexus. Read More

Other news to note for April 1, 2020

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Amgen, Astellas, Azurrx, Cardiol, Citius, China Shijiazhuang Pharmaceutical, Daiichi Sankyo, Danaher, Daré, Diffusion, Editas, Eisai, Emergent Biosolutions, Eyepoint, Flexion, GE, Immunitybio, Innovation Pharmaceuticals, Macromoltek, Modalis, Novavax, Novellus, Ocumension, Oramed, Ostrich, Paratek, Regenxbio, Sanbio, Seikagaku, Soleo Health, Sorrento, Ultragenyx, Vaccibody. Read More

Regulatory actions for April 1, 2020

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Acasti, Aveo, Concert, Cytodyn, Diurnal, Faron, Mallinckrodt, Mesoblast, Novoteris, Orchard, Y-mabs. Read More

Regulatory front for April 1, 2020

The latest global regulatory news, changes and updates affecting biopharma. Read More

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