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BioWorld Science

Aug. 23, 1996

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More tachykinin NK1 antagonists reported by Sandoz

Protein Polymer Technologies and Ethicon sign R&D agreement

Dyad granted U.S. patent for oligonucleotides

Kanebo and Ontogen to codevelop cell adhesion factor inhibitor

Dusa completes phase IIb for ALA PDT

Genzyme's Seprafilm approved by FDA

Repel proved effective in preclinical studies

Takeda describes cephem antibacterial agents

Xoma granted permission to commence phase III for rBPI21

Parke-Davis and Xenova begin evaluation of novel antibacterial

Sequus and Torrex Pharma sign Amphotec marketing agreement

Solvay to copromote Famvir in U.S.

Vistide marketing collaboration established

Isis now fully owns fomivirsen

GEM-132 enters phase I safety and pharmacokinetic trial

SmithKline Beecham describes protease inhibitors

SR-3775: Promising candidate for cytomegalovirus disease treatment

Roxane Laboratories has begun U.S. nevirapine distribution

Dainabot seeks Japanese approval of Norvir

Norvir approved by Canadian authorities

Epivir approved for European market

Zerit launched in U.K.

Zithromax demonstrates prophylactic effect against MAC in AIDS patients

Biaxin shown to prolong longetivity in AIDS patients

Protease inhibitors from Sankyo

KF-20444: Kyowa Hakko's novel antirheumatic agent

Hyanalgese-D demonstrates negative efficacy in U.S. phase III trial

Cyclooxygenase-2 inhibitors from Merck Frosst

Cyclooxygenase-2-inhibitors described by Japan Tobacco

Alexion's C5 complement inhibitor effective in murine lupus model

North American Vaccine/Abbott DTaP marketing agreement

Cel-Sci and U.S. Navy collaborate on malaria vaccine

Immunomodulating peptides from BioChem Pharma

Taiho discloses antitumor nucleoside drugs

Japanese investigators describe antileukemia activity of drupangtonine

Phase I pharmacokinetic study of asulacrine initiated

Fareston launched in the U.K.

European approval sought for new Rebif indications

AltaRex awaits Canadian approval to begin Ovarex phase II/III trials

Progenic's GMK undergoes phase III clinical trials

MDX-210 efficacy/safety trial begins in U.K.

IDEC-Y2B8/IDEC-C2B8 combination undergoes phase I/II

C242-DM1: Promising new approach to colorectal cancer treatment

Imutec/NaPro BioTherapeutics sign research agreement

Study indicates ISIS-3521/CGP-64128A inhibits tumor growth

Shionogi reports ras transformation inhibitor

Farnesyl transferase inhibitors from Pierre Fabre

NeXstar describes ELONA and significance for VEGF inhibitor development

VIMRxyn to undergo phase I in glioma patients

Antineoplastic agents from Japan Energy

Accelerated drug development program for Oxi-104

Ethyol extended labeling approved

Lisofylline undergoes phase III in cancer patients

Glaucoma diagnostic under investigation in Germany

Aredia earns U.S. approval for new indication

Osteocalcin study findings reported

Indian hedgehog molecule's role in cartilage and bone development

Yamanouchi and PT CarbaPharma describe cathepsin L inhibitor

Eisai's squalene synthase inhibitor and prodrug

New hypolipidemic agent from Schering-Plough

Metachol distribution agreement

CCK-A agonist from Glaxo Wellcome

RIIbeta: Potential antiobesity drug target

Hematopoiesis-stimulating compounds from Nycomed Pharma

Nicotine nasal spray codevelopment agreement

CeraMed Dental: Dentsply/CeraMed joint venture

NeoRx's Verluma approved for U.S. market

Calypte HIV-1 Urine EIA test approved by FDA

FDA grants marketing approval for Biopool's Chromolize tPA Assay Kit

La Jolla seeks patent on MI risk factor identification method

H. pylori test marketing agreement

MicroCarb granted U.S. patent for antibodies used in VeroTest

Palatin Technologies receives SBIR grant for diagnostic tool research

OncorMed and Zeneca Diagnostics collaborate on cancer diagnostics

Cyogen issued U.S. patent for PSMA

Organobismuth derivative contrast agent from Nissan Chemical

Ciba-Geigy describes oligonucleotide diagnostic agents

Draxis Health seeks Canadian approval of modafinil

Allelix Biopharmaceuticals reports selective M1/M2 receptor ligands

Zeneca files for U.K. marketing approval for Seroquel

Allelix describes dopamine D4 ligands for schizophrenia

5-HT1D antagonists claimed by SmithKine Beecham

Organon and Chiron sign research agreement

Organon and Signal sign drug development agreement

Dynatronics/Life-Tech sign distribution agreement for iontophoresis products

Data on Sterizone to be presented at scientific meeting

Zila to acquire Bio-Dental Technologies

Positive study results reported for CytoTherapeutics' encapsulated hCNTF device

Biogen signs Avonex distribution agreements

Study indicates that estrogen may delay Alzheimer's disease onset

Study of senile plaques guide Alzheimer's development

Nymox Pharmaceuticals present positive results from AD7C trial

UPF-596 described as a novel glutamate antagonist

BASF reveals NMDA and AMPA antagonists

Nitric oxide synthase inhibitors from Merck & Co.

The Wellcome Foundation claims nitric oxide synthase inhibitors

Further nitric oxide synthase inhibitors from Chugai

Hoechst Marion Roussel launches Allegra on U.S. market

Proventil HFA given FDA approval

PAF antagonist Y-24180 enters phase III

FR-173657: Fujisawa's bradykinin B2 antagonist

Forest's Infasurf earns approvable status

Usherdex-4 and other dextrans covered under U.S. patent

New calcium entry blocker described by Italian researchers

Endothelin ETA inhibitors described by Roche

Roche discloses ETA antagonists for circulatory disorders

Ciba-Geigy claims endothelin converting enzyme inhibitors

More endothelin converting enzyme inhibitors from Warner-Lambert

Apolipoprotein A-IV as atherosclerosis treatment

European patent protection issued for Hyal's hyaluronan technology

Phospholipase A2 inhibitors from SmithKline Beecham

Roche reveals EGF-R tyrosine kinase inhibitors

Thiazolidinone compounds as antianginal agents from Sankyo

Adenosine reuptake inhibitors from Kyowa Hakko

Carvedilol approved for CHF indication in Spanish market

BMS-186716: Bristol-Myers Squibb's ACE/neutral endopeptidase inhibitor

Santen reveals neutral endopeptidase inhibitors

BioChem Pharma claims thrombin inhibitors for coagulopathies

More thrombin inhibitors from BioChem Pharma

Corvas describes Factor Xa inhibitors

Fibrinogen antagonists in SmithKline Beecham's pipeline

Terumo claims antithrombotic/antiallergy agents

BTG and the New England Medical Center sign marketing agreement

EDAP signs license agreement for microwave technology

Boston Scientific to distribute Urologix technology

Bioniche seeks U.S. approval to begin Cystistat clinical trials

McGill University researchers improve safety of cell therapy

Tritec approved for U.S. market

Hepatitic C infection drug discovery alliance formed

Humalog launched on U.S. market

Pramlintide shows positive safety/efficacy profile in phase II

Johnson & Johnson continues pramlintide collaboration

Alteon initiates phase III trials of pimagedine

Update on Biotech Holdings' Diab II

Humatrope approved for new indication in U.S.

Astra's Atmos launched in Sweden

Columbia Laboratories granted U.S. patent for Crinone technology

Potential tachykinin NK1 antagonists from Merck & Co.

Erythromycin A 9-O-oxime derivatives from Zambon

STV: Possible antituberculosis and autoimmune disease therapy

Novel antitumor compounds claimed by Kyorin/Sagami

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