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BioWorld Science

Oct. 18, 1996

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Merck & Co. reveals new series of tachykinin antagonists

Barr re-introduces generic drug for pain

Tentative FDA approval for generic analgesic

New antimigraine agents disclosed by Merck & Co.

Faulding to distribute Carrington's hydrogel wound dressings

Patent coverage for Demeter BioTechnologies wound-healing proteins

Proceedings report improved patient outcome with ADCON-L

Pfizer discloses polycyclic ether antibiotics

Bristol-Myers Squibb obtains rights to Kyorin antibiotic

Antimicrobial collaboration between Human Genome Sciences and Pharmacia & Upjohn

Neuprex enters pivotal trials

Glaxo Wellcome claims antiviral agents with RNA virus specificity

RiboGene receives grant for antiviral compounds based on PKR

Retroviral zinc finger inhibitors as anti-HIV agents

Norvir now available in U.K.

Shionogi begins clinical trials with novel reverse transcriptase inhibitor

Pivotal trial of thalidomide in AIDS patients completed

South and Central American development and distribution agreement for Remune

Albendazole introduced in the U.S. for two parasitic infections

University of North Carolina/Macronex research cytokine inhibitors

Washington University's MCP regulates complement activity

New cPLA2 inhibitor from Merckle

Dimethaid seeks approval for treatment for arthritic pain

Lyme disease vaccine claimed by University of Minnesota

Magainin discloses LAP for microbial infections

University of Texas discloses OMPs for immunotherapy

New immunosuppressants disclosed by Merck & Co.

Potential Chlamydia vaccine effective in preclinical studies

Spotlight on antiinfective vaccine research in the U.S.

Japanese researchers report new antitumor antibiotics

Kyowa Hakko reports antiestrogenic agents

HER2/neu peptide fragment provokes immune response against tumor cells

Chemokine/cytokine combination effective for tumor therapy

Broader role of VEGF in tumor growth proposed

Tyrosine kinase inhibitor developed by Cephalon and TAP enters clinical trials

VCAM-1 inhibitors from Sagami

Banyu reports natural antitumor agent

New antitumor agents from Sagami

Eisai claims RXR agonists

Natural antitumor indanone reported by Sagami

Targeted Genetics receives grant for its HER-2/neu oncogene inhibitor

Isis antisense compound and analogues covered by U.S. patent

Sugen-Allergen collaboration in ophthalmic diseases

Revolutionary treatment for nearsightedness enters pivotal trials

Lilly claims compounds for women's health

Anorexigenic dihydropyridine compounds from Bristol-Myers Squibb

Antiobesity proteins described by Lilly

Warner-Lambert describes NK2 antagonists for obesity

New NPY antagonists from Warner-Lambert

U.S. patent covers Celtrix's SomatoKine

Cangene acquires iron chelator from Apotex

Akzo patents new method for imaging infections

Schering AG discloses DTPA derivatives for diagnostic use

RIGScan CR49 highly effective for locating hard-to-find cancer

Digene-Cytyc alliance focusing on cervical cancer

Adeza receives grants to develop assays for fertility and pregnancy

Palatin receives funds to develop somatostatin analogue as cancer diagnostic

NIH seeks licensees for method for detecting TSEs

Antipsychotic agents from Asahi Chem.

Potential new class of neuroleptics discovered at NYU

Buckminsterfullerene inventors receive Nobel Prize in Chemistry

Peptidomimetic compounds disclosed by University of Pennsylvania

Regeneron-Pharmacopeia drug discovery collaboration

Funding for Genetronics' electroporation delivery technology

Middlesex Sciences changes name

Pall and Gelman open discussions

ICN Chinese joint venture

Epoch-VIMRx alliance

Fujisawa to transfer rights to Astra products

Ingenex Company Profile

PDR Meeting

GV-4000 available for licensing

Berlex suit relating to Avonex dismissed

Promising clinical results with MS vaccine

Seventeenth approval for Rilutek

AM-424 available for licensing

Lilly's benzimidazole compounds for beta-amyloid peptide-associated disorders

Huperzine A analogues claimed for treatment of AD

Neuroprotective calpain inhibitors from Warner-Lambert

OTC switch recommended for Nasalcrom

Schering-Plough's Claritin line expanded

Leukotriene antagonists from Sankyo

Menarini studies LTD4 antagonists for asthma Rx

CGP-57698: Follow-up compound to iralukast reported by Ciba-Geigy

New FLAP inhibitor presented by Abbott

PAF synthesis modulators described for inflammation

First approval for Astra asthma product

Salmeterol deemed safe with proper use

Arris-Bayer collaboration identifies candidate tryptase inhibitor

Targeted Genetics receives grant for manufacturing cystic fibrosis product

PRAISE trial demonstrates safety of calcium channel blocker in severe heart failure

Antihypertensive combination cleared for marketing in the U.S.

First low-dose hydrochlorothiazide product approvable

Tsumura discloses agents for atherosclerosis

GenVec licenses human iNOS gene from University of Pittsburgh

Benzimidazole derivatives for use in heart failure

BASF reports on novel thrombin inhibitors

Antithrombotic prostaglandin analogue revealed by Asahi Glass

Antiplatelet agents from Taisho

Servier selects TxA2 antagonist for further study

Merck persists in the search for BPH therapeutics

New alternative available for BPH

Gastric antisecretory agents disclosed by Il-Yang

Astra-CSL collaboration for H. pylori immunotherapeutic

LTA4 hydrolase inhibitor effective in ulcerative colitis

Tokyo Tanabe discloses agents for the treatment of diarrhea

Joint venture to develop Exten's artificial liver technology

RiboGene receives further funding for HCV

Medical breakthroughated to HEV vaccines and diagnosis reported

Novo Nordisk enters collaboration on PTPase inhibitors

JT and Tularik to develop new antidiabetic agents

Serono's recombinant human growth hormone approved

Menorest approved in Belgium

First and only Estrophasic oral contraceptive approved

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