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BioWorld Science

April 30, 1997

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NCI identifies compounds effective against aggressive human tumors

Preclinical results of IL-12 for chronic viral disease

Didox/Trimidox demonstrate antiretroviral activity in murine model

BMS-200475: profile of a novel anti-hepatitis B compound

ISIS-5320: preclinical study results

Novel cardiac antiischemic agents disclosed by Kanebo

Endothelin antagonists reported by Kowa

Kissei prepares smooth muscle cell proliferation inhibitors

GABA-B antagonists from Novartis

Roche discloses human renin inhibitors

Potent, selective and orally active COX-2 inhibitors from Parke-Davis

Guidant and Neuroperfusion to further develop device for stroke

Preclinical studies with GPI-2A reported by Genesys Pharma

New treatment for Wilson's disease now available

Abbott discovers potent topical immunosuppressant with minimal systemic effects

Schering-Plough develops potent farnesyltransferase inhibitor

Vertex designs potent, conformationally restricted HIV protease inhibitors

Calcium antagonist shown to cause left ventricular hypertrophy regression

Astra: Q1 1997 highlights

Centocor: Q1 1997 highlights

Genzyme Tissue Repair: Q1 1997 highlights

Penederm: Q1 1997 highlights

Xoma: Q1 1997 highlights

Positive preclinical results for T-330 in animal models of gastric ulcers

Dendrimer polyanions with activity against RSV

Advances in novel drug delivery at Inex

Company Profile: Kimeragen

Company Profile: MethylGene

Cambridge NeuroScience achieves new position of strength

Potent inhibitors of HIV-1 and other enveloped viruses reported

Trimeris prepares potent peptide inhibitors of viral fusion

Fluvastatin safe and effective in hypercholesterolemic patients on probucol