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BioWorld Science

May 22, 1997

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Isis reports positive safety and efficacy profile for fomivirsen

Celgene describes TNF/PDE inhibitors

Atypical neuroleptics from Merck KGaA

Chiroscience prepares new class of peptidyl MMP and TNF-alpha inhibitors

Glaxo Wellcome describes optically active pyrimidine useful as analgesic and anticonvulsant

Pfizer reports prodrugs of NMDA antagonist

Diaziridinylpolyamines as anticancer agents claimed by U. of Maryland

Na+/H+ exchange inhibitors reported by Hoechst

VX-497: selective IMPDH inhibitor with potent immunosuppressive properties

Onyx reports clinical results of anticancer viral therapeutic at ASCO meeting

Antiplatelet effects of arbidol

Mylan receives FDA approval for generic etodolac

NMDA antagonist/opiate combination provides superior analgesia to morphine alone

Antibodies to interferon gamma alone and in combination for arthritis and SLE

UR-12670 effective in rat model of endotoxic shock

Encouraging results reported for ImClone's lead cancer therapeutic agent

Preliminary phase II and phase I/II results for Allovectin-7

Interim results with Pharmacyclics' Gd-Tex reported at ASCO

Pharmacyclics reports phase I results for Lu-Tex

FDA reschedules review date for Heart Laser

Malononitrilamides associated with potent immunosuppressive effects in animal models

Phase I results with Isis antisense anticancer drug reported at ASCO

Enrollment complete for phase II trial of lisofylline in AML

North American Vaccine cleared to initiate trials of meningitis vaccine

First launch for Quadramet

Alora launched in U.S.

GenESA System deemed approvable

Disappointing phase III results for Bayer anti-TNF antibody

Molecumetics and Asahi enter anticoagulant collaboration

Results from a comparative study of olanzapine and risperidone reported

Oxford GlycoSciences receives U.K. approval to commence trials on novel nucleoside analogue

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