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BioWorld Science

Sep. 18, 1997

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Growth hormone antagonist enters phase II

Alpha1-adrenoceptor antagonists improve symptoms of BPO, BPH in clinical studies

GEM-92 enters clinical trials for AIDS

KMD-3213: a newer alpha1-adrenoceptor antagonist for BPH

KRN-4884 active in several preclinical models of hypertension

Separation of antiobesity and antidiabetic effects of beta3-adrenoceptor agonist established in rats

Anticonvulsant profile of two new GABA uptake inhibitors

Role of osteoprotegerin in skeletal metabolism elucidated

New anthraquinone interacting with telomeric G-quadruplex DNA

3-D database search at Schering-Plough leads to potent, selective FPT inhibitors

Dual ACE/NEP inhibitors described by Zambon

Fujisawa discloses new PDE IV/TNF inhibitors

Known antidiabetic agent modulates glucocorticoid response in osteoclasts

Retinoid-like compounds from Allergan

FDA panel recommends approval of Anesta's Actiq for cancer pain

Efavirenz/indinavir combination shows efficacy in phase II

Novel osteoclast resorption inhibitor isolated by Swiss investigators

New raloxifene analogue from Lilly is a potent SERM

Potent and selective N-type calcium channel blockers for stroke

Oxford GlycoSciences' OGT-719 enters clinical testing

TheraTech and Astra sign agreement for Androderm distribution

Dopamine D1/D2 coactivation maximizes metabolic responses in obese mice

October launch for Zanaflex in U.K.

U.S. introduction for FemPatch

Asta Medica and Wyeth-Ayerst agreement for epilepsy drug

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