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BioWorld Science

April 27, 1998

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Company Profile: Vectagen

Lamivudine consistently effective as a treatment for hepatitis B

Montelukast shows promise in the treatment of pediatric asthma patients

Company Profile: SignalSite

SciClone reacquires rights to Zadaxin in Italy

Generic controlled-release carbamazepine approved in U.K.

Ofloxacin-impregnated beads demonstrate efficacy in the prevention of osteomyelitis

LY-303366: antifungal activity in a murine model of invasive aspergillosis

Nitroquinoxalinediones for inhibiting neuronal cell death

Bronchodilating and antiinflammatory agents claimed by Nikken

Genometrix and GeneMedicine embark on high-throughput screening effort

Elan signs definitive agreement to acquire Carnrick

Pacific will begin safety trial of BOPP photodynamic therapy

ImmuLogic: Q1 1998 highlights

Sparta licenses drug delivery technology for temozolomide to Schering-Plough

Novo Nordisk sells Seroxat marketing rights to SKB

Oxandrin approved in South Korea and the Azerbaijan Republic

Cubist, Neurogen collaborate on antiinfective drug discovery

Crystaal in-licenses Neurex's Corlopam

Amgen: Q1 1998 highlights

New hirudin option now available in U.K.

Baccatin derivatives with antitumor activity developed at Tanabe Seiyaku

Cathepsin inhibitors under study at Nippon Chemiphar

Toyama focuses on cephalosporins, particularly anti-MRSA compounds

Oral levosimendan effectively substitutes for i.v. inotropic therapy

Roberts acquires Pentasa marketing rights from HMR

Dofetilide exerts atrial positive inotropic effect in AF patients following cardioversion

Glaxo Wellcome terminates clinical trial for septic shock agent

New NK1 receptor antagonist ineffective against postherpetic neuralgia

FDA advisory committee will meet to discuss Thyrogen NDA

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