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BioWorld Science

July 13, 1998

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Biapenem: safe and tolerable antibiotic for elderly subjects

Characterization of MAb 18B7, a candidate for human studies

Absence of cardiodepressive effects with beraprost

Fentanyl delivery via SmartMist provides effective analgesia

L-Ornithine-L-aspartate: safe treatment for cirrhosis and chronic hepatic encephalopathy

WR-238605 effectively protects against malaria infection in volunteer study

MacroChem and American Home Products sign collaborative agreement

Cephalon and Medtronic renew ITB copromotion agreement

Regressin holds promise for a wide range of cancers, new data indicates

Theragyn phase III testing will begin in U.K.

Phase I/II trial data released for P&U protease inhibitor

Impaired glucose tolerance and diabetes mellitus in AIDS patients treated with protease inhibitors

COL-1492 can be used several times daily without safety concerns

PRO-2000 prevents infection by STD pathogens other than HIV

Preclinical and clinical profile of (+)-calanolide A, a novel NNRTI from a natural source

Genome Therapeutics establishes licensing agreement with Princeton University

Addition of Remune to HAART leads to enhanced viral suppression

WF10, a unique AIDS treatment alternative evaluated in the clinic

Collagenase inhibitors in the pipeline at British Biotech

Merck's new tachykinin receptor antagonists useful for pain, inflammation, etc.

Subtype-selective MMP inhibitors patented by Agouron, Syntex

Antagonists of neurotrophin activity described by Allelix for pain, epilepsy and AD

New thrombin inhibitors synthesized at Merck & Co.

M-16049 compared to troglitazone for ability to improve insulin resistance

Effects of KRP-297 on progression of diabetes in db/db mice

Effects of new SGLT inhibitor on insulin and glucose in Zucker diabetic fatty rats

Aldose reductase inhibitor from Nippon Zoki effective in rats with diabetic neuropathy

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