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BioWorld Science

Sep. 4, 1998

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A reduced deacetylated metabolite of FK-317 is responsible for antitumor activity

Coadministration of PNU-156765 and antiandrogen for prostate cancer

Omapatrilat effective therapy for patients with chronic heart failure

IND application for NeXstar antiangiogenesis drug approved by FDA

MacroChem's treatment for erectile dysfunction demonstrates safety and efficacy

Muse in combination with Actis in the treatment of male impotence

Regeneron receives milestone payment from Sumitomo related to BDNF development

Sonus files amendment to EchoGen NDA

NK2 antagonist saredutant prevents NKA-induced bronchoconstriction in asthmatic subjects

FDA approves Gemzar for first-line treatment of non-small cell lung cancer

Clinical trials commence for Calydon's viral therapeutic for prostate cancer

Biotech Australia announces encouraging early clinical trial results with leg ulcer treatment

Neuroprotective and antioxidant phenazines designed at Nippon Chemiphar

Antimicrobial polypeptides claimed by Fujisawa for infectious diseases

P&U, U of Maryland describe inhibitors of kynurenine aminotransferase

Scripps patents guanine derivatives with immunostimulating activity

Genetix awarded grant for antiangiogenic gene therapy development

Cortech to form new European company to develop PSI technology

FDA clears Intron A for pediatric chronic hepatitis B

Label expansion recommended for Photofrin in U.S.

Spotlight on treatment of substance abuse disorders

Taisho discovers potent and selective CRF1 receptor antagonists with anxiolytic effects

Potent mixed delta/mu-opioid agonist identified by Glaxo Wellcome/Delta team

Merck KGaA synthesizes new PDE V inhibitor with potential for treating ED

DW-2282: active enantiomer of DW-2143 and potent antitumor agent

Alprostadil alfadex is a promising treatment for ED

LLPGE1 evaluated in pilot study; findings will be applied to future studies

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