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BioWorld Science

Sep. 25, 1998

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Novel use proposed for EGCg: inhibition of HIV-1

ICAAC news flash: Lilly presents phase I results for glycopeptide antibiotic

SB and LG Chemical profile their broad-spectrum fluoroquinolone at ICAAC

New gastric prokinetic agents in the Zeria pipeline

Kissei discovers series of vascular smooth muscle cell proliferation inhibitors

Warner-Lambert team prepares inhibitors of bacterial signal transduction

Broad-spectrum antiviral agents related to phosphonoformic acid patented by Astra

Novel cephems from Meiji Seika active against resistant bacterial strains

Organon designs nonpeptide thrombin inhibitors mimicking D-Phe-Pro-Arg

ZK-200775: a water-soluble AMPA antagonist with an excellent pharmacological profile

Negative results reported for ImmuCell's TravelGAM; development focus now on DiffGAM

HSR-903 shows excellent antibacterial activity, intracellular penetration in in vitro studies

Acquisition of Hexagen by Incyte completed

Clinical results support use of nesiritide over dobutamine in acute CHF

Head-to-head comparison of two HBV vaccines

KRM-1648 combinations show strong, rapid and long-lasting antimycobacterial activity

Administration of multiple high doses of S-4661 does not affect safety, pharmacokinetics

IB-643 more effective than AmB in treating systemic murine candidosis

Profile of activity of new antifungal antibiotic presented by Fujisawa at ICAAC

Oxigene updates Neu-Sensamide development status

Vanguard discontinues development of psoriasis drugs

HMR grants Matrix rights to anticancer agent about to enter phase II

Astra returns rights to ALX1-11; Allelix to aggressively pursue development

In vitro and in vivo activity of S-34109 against Chlamydia and MRSA

Zanamivir results presented at ICAAC; two more regulatory filings announced

Investigational anti-HIV drug offered through early access program

P&U explores modifications to linezolid; new, more active oxazolidinones result

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