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BioWorld Science

Nov. 9, 1998

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Further evidence of the potential utility of BO-653 in restenosis

Corixa invests in, works with ImmGenics to develop high-potency monoclonal antibodies

GBC-590 effective in murine model of treatment-resistant pancreatic cancer

Pyrazolopyrimidines useful as analgesics prepared at Otsuka

Novel series of mast cell chymase inhibitors in development at Teijin

NK-26588: new inhibitor of iNOS produced by Streptomyces sp.

Kyowa Hakko patents new adenosine A2A antagonists

Avasimibe a protagonist at the AHA's 71st scientific sessions

Potent series of bradykinin antagonists disclosed in patent literature

Pfizer prepares metabolically stable adamantane derivatives

Novel 5-HT1B receptor antagonist presented this week by Astra Arcus

Eplerenone effectively treats hypertension and aldosterone-induced damage in CV organs

Selective M2 receptor antagonist from Schering-Plough with potential in AD

Oral antioxidant improves endothelial function in diabetic men

Centrally selective nAChR ligand from R.J. Reynolds considered Alzheimer's disease candidate

APLAUD study evaluates SB-214857 in patients with coronary artery and cerebrovascular disease

Effects of new free radical scavenger MDL-100002 in embolic stroke

Dura and Spiros receive FDA review letter on Albuterol Spiros indicating need for additional study

Novel proteasome inhibitor effective in animal model of stroke

Droloxifene effects on lipid parameters evaluated in healthy postmenopausal women

In vitro and in vivo pharmacology of CP-465022 presented at neuroscience meeting

Ribozyme initiates phase I clinical trials of Angiozyme

Sanguine reports significant breakthrough in the development of blood substitute

NPS-2390: representative of a novel class of potent and selective group I mGluR antagonists

J&J announces merger of subsidiary with DePuy

Neuroprotective agents with dual NOS-inhibitory and antioxidant effects synthesized at French lab

New 5-HT1A receptor antagonist from Astra Arcus undergoes extensive preclinical testing

United Therapeutics licenses Cortech's elastase inhibitor

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