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BioWorld - Sunday, December 7, 2025
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BioWorld Science
Jan. 7, 1999
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Sugen awarded U.S. patent for transcript imaging technology
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Series of Na+/Ca2+ exchange inhibitors for ischemic disorders from Taisho
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Potent thrombin inhibitors with heterocyclic structure synthesized at Lilly
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ACAT-inhibitory urea derivatives claimed by Mitsubishi for lipid disorders
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S-19777: novel ET antagonist of microbial origin
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Carbapenems in development at Sankyo
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Xanthine oxidase inhibitors for hyperuricemia, gout described by Yoshitomi in patent literature
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U.S. patent issued to Millennium covers novel forms of caspase 8
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Anika outlines plans for 1999 as regards product pipeline
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Proleukin receives orphan drug status for two new indications
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New antiobesity target a focus of attention at recent Japanese meeting
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New family of gene-regulating enzymes discovered by Signal, Hebrew University
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FDA approves OTC status for Elan's nicotine patch
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Combinations of K-12 and other anti-HIV compounds tested in vitro for synergy
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Phase II trial results published for repaglinide for treatment of type II diabetes
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PSC-833 modulates the tumor disposition of vinca alkaloids in vitro and in vivo
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More anti-HIV, antimalarial agents available for licensing from NIH
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Nonpsychoactive, neuroprotective cannabinoids available for licensing from NIH
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CNI-1493 attenuates hemodynamic and cytokine responses to LPS in rats
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Favorable preclinical, clinical results continue to encourage development of ABT-378
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AxyS initiates phase I clinical trial of APC-2059 for treatment of psoriasis
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Fujisawa obtains Japanese marketing rights to Zeneca's atypical antipsychotic quetiapine
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Prodrug glucocorticoid NM-135 displays potent antiinflammatory activity, good side effect profile
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Ilex and Symphar begin phase I studies of SR-45023A
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Interneuron receives milestone payment from Lilly under Prozac agreement
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Bristol-Myers Squibb seeks approval for new antibiotic for respiratory and other infections
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Remacemide provides neuroprotection during CPB
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Photofrin approved in U.K. for palliative treatment of esophageal cancer and late-stage lung cancer
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