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BioWorld Science

March 19, 1999

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Caspase inhibition by Ac-YVAD-cmk enhances nigral transplant survival

Phase III results support use of memantine in dementia

Cerebral metabolic consequences of NOS deficiency in null mice

Cardiovascular and Renal Drugs Advisory Committee will discuss Betapace at April meeting

Pharmacological profile of A-216546, a novel endothelin antagonist

Novartis discusses short-term pipeline at annual press conference

Licensing opportunity from NIH: infectious papillomavirus pseudoviral particles

Shaman refines restructuring process, maintains new focus on botanical products

Biovector collaborates with Chiron and Bayer on DNA delivery applications

Structural Bioinformatics achieves research milestone

Clinical trials begin for IFN-alpha gene therapy in cancer patients

SciClone receives additional Zadaxin marketing approvals in Singapore and Vietnam

Plant-produced cancer vaccine enables mice to survive non-Hodgkin's lymphoma

Warner-Lambert patents new series of irreversible TK inhibitors

uPA-uPAR antagonists in development at Roche for tumors and tumor metastasis

RCT reports synthesis of novel antibiotics active against resistant pathogens

Pfizer discloses selective hydroxamic acid-based MMP-13 inhibitors

Kynurenine pathway enzyme inhibitors from P&U for neuropathological disorders

Pediatric clinical trials of exisulind expanded; analysis of phase III adult trial data continues

Licensing opportunity from Yeda: vanadyl ion carriers for the treatment of diabetes

Genzyme Transgenics and Millennium BioTherapeutics collaborate on transgenic biotherapeutics

Antex Chlamydia vaccine shows promise in animal study

Gliatech initiates new R&D program for antiinflammatory MAbs

Arsenous acid for relapsed APL under evaluation in China

Vion seeks permission to begin clinical trials of TAPET vectors

Further marketing authorizations granted in Europe for Muse

CPMP supports new labeling, new indication and new strength of Gonal-F

Japanese market clearance obtained for Casodex 80

Preliminary InTIME-II results point to equivalence of lanoteplase and alteplase in AMI

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