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BioWorld Science

March 18, 1999

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L-arginine induces apoptosis by NO synthase pathway

Pasteur Merieux Connaught enters agreement to develop jet injectors for infuenza vaccines

Combination therapy with delavirdine and zidovudine in AIDS

Antioxidant and NOS inhibitor synergistically protective in cerebral ischemia

Neurocrine's APL compound enters phase I trial for IDDM

Alza acquisition of Sequus approved

Clinical trials of needle-free delivery of DNA vaccine begin

InKine completes enrollment of first pivotal phase III clinical trial of Diacol

Rapamycin demonstrates potential in asthma

Insmed announces phase II study results in type II diabetes; company awarded SBIR grant

Mouse study provides preliminary indications of the antitumor efficacy of AR-209

Glutamate antagonists and anticonvulsants developed at RPR

Immunomodulatory effects of sinomenine, an alkaloid compound of plant origin

Peripheral and Central Nervous System Drugs Advisory Committee meets in April

Celgene describes new series for reducing TNF-alpha levels

Available for licensing from Yeda: peptide compounds for inhibiting the allergic response

Selective beta3-adrenoceptor agonists patented by Asahi Chemical

Novel antitumor BE-45985 compounds isolated and characterized by Banyu

Benzamides with low nanomolar affinity for 5-HT4 receptors

Patent issued to Boehringer Mannheim (now Roche) covers novel approach to cancer therapy

Steroid-piperazine compounds for bone disorders discovered at Chinese university

Novel platelet aggregation inhibitors developed by Chinese research team

NAS supports clinical testing of marijuana, development of new delivery mechanisms

First approval received for new insomnia Rx

Effects of raloxifene on coronary vasculature studied in vitro: results presented at ACC meeting

Phase III data indicate strong analgesic potency of Roberts' Dirame

FDA approves Prosorba Column for use in rheumatoid arthritis

Inhibition of native and bFGF-induced angiogenesis by ADMA

Aspirin inhibits cytokine-induced endothelial expression of proinflammatory adhesion molecules

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