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BioWorld Science

March 31, 1999

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Results of Onconase trial in malignant mesothelioma reported

Landmark study demonstrates successful example of gene therapy for pain control

Postmenopausal syndrome continues as focus of R&D at Lilly

Nonpeptide tachykinin antagonists: preparation and use described by Lilly

Multiple pharmacological effects reported by Egis for new AMPA receptor antagonists

Ono discloses PPARgamma modulators for metabolic disorders

FDA approves expanded use of Epivir in infants, children and adolescents

Positive findings from VX-497 studies presented at international antiviral research conference

Australian authorities approve Relenza for treatment of influenza

Liposomal antiseptic enters clinical testing at Mundipharma

Studies on BTK inhibitors expected to result in discovery of new anticancer drugs

NDA for frovatriptan accepted for FDA review

Potent new SERM related to raloxifene presented at ACS meeting by Lilly

Kyorin describes production, synthesis and structure of novel antibacterial substance

Merck develops potent, short-acting, orally active GH secretagogues

Pharmacokinetics and pharmacodynamics of VPA-985 in healthy volunteers

Novel beta2-adrenoceptor agonist isolated from a marine sponge by Kirin Brewery

O6-Benzylguanine shows potential for oral efficacy in humans

No pharmacodynamic or pharmacokinetic interactions in humans for OPC-41061 + diuretics

Dual LTD4/TxA2 antagonist demonstrates superior bronchodilating efficacy in animal models

In vitro and in vivo profile of SB-265805 discussed at European microbiology meeting

Emoxipin analogues studied by Russian team in animal models of infection

International team identifies myristic acid analogues with antipicornaviral activity

Lovastatin now available for expanded use in U.S.

Aspirin should not interfere with the cardioprotective activity of terbogrel

Excellent efficacy reported with topical ciclesonide in patients with allergic rhinitis

Effexor XR demonstrates long-term effectiveness in treatment of GAD

S-0509 exhibits potent gastric acid antisecretory effects in animal models