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BioWorld Science

April 23, 1999

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Cognitive effects of three new antiepileptic drugs examined

New beta blocker facilitates beating-heart surgery

Epitope receives CE Mark for OraSure, federal supply authorization in U.S.

GPC and MorphoSys collaborate on human therapeutic antibody program

Cortex's schizophrenia drug enhances cognitive function

Pharmadigm updates DHEA product development

Company Profile: Phytopharm

Immunotherapeutic method of treating viral respiratory disease available from NIH

CXCR receptor antagonists in development at SB for chemokine-mediated disorders

Malonic acid-based MMP inhibitors with novel binding properties developed at Roche

SmithKline Beecham synthesizes pharmaceutically active integrin receptor antagonists

Merck & Co. discovers new series with antithrombin effects

Potent and selective COX-2 inhibitors described in recent patent literature by Novartis

University of Michigan team establishes role of IL-17 in pathogenesis of acute lung injury

Moxonidine metabolite synthesized by Lilly and assessed in SHR

IDEC-131, an inhibitor of B-cell activation for the treatment of autoimmune disorders

Hybridon describes mixed-backbone anti-MDM2 antisense oligonucleotide active in vivo

Avandia approved in Mexico, approval recommended in U.S.

Pruritus: a potential new application for kappa-opioid agonists

New EAA antagonist from Lilly effective in animal model of TBI

Antisense oligonucleotide against alpha4 integrin improves paralysis in animal model of MS

DuPont presents somatostatin analogues YH-137 and YH-138 with antiangiogenic effects

News from FASEB: novel activators of CFTR currents developed at European universities

HP-228 reduces obesity and insulin resistance in animal models

Abbott obtains marketing rights to Meiji cephalosporin in several major markets

Subject of Alkermes-Janssen collaboration revealed; compound advancing to phase III trials

Metabolism and disposition of novel anti-HIV agent studied in isolated rat liver

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