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BioWorld Science

June 21, 1999

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Icos reports results from LeukArrest clinical trial in hemorrhagic shock

Epimmune and Cytel to merge

Gliatech files IDE for ADCON-L in breast surgery

Corixa teams up with Japan Tobacco on lung cancer vaccine research

Warner-Lambert and Pfizer expand marketing collaboration

FPTO, a novel cardiovascular agent acting via NO pathways

Role of imidazoline receptors in hypertension

Parathyroid hormone plus estrogen restores bone density to normal levels in osteoporotic women

Dutasteride suppresses DHT levels more effectively, consistently than finasteride

Trimegestone is potentially superior to MPA for HRT

AHP launches ReFacto hemophilia A treatment in the U.K.

Japanese investigators explore natural sources for novel antimalarial agents

Canadian authorities have approved Ligand's Panretin Gel for KS

Antifilarial efficacy of PF-1022A demonstrated in gerbil model

Carbohydrate anticoagulants with low sulfate content result from European collaboration

New paclitaxel derivatives with broad anticancer activity developed at Xechem

New antidiabetic agent presented by Bayer scientists this week in San Diego

BASF synthesizes new endothelin receptor antagonists for cardiovascular and other disorders

Chemokine receptor antagonists identified by Teijin and CombiChem

New therapeutic strategy presented at ADA: dipeptidyl peptidase IV inhibitors

Merck describes new selective alpha1a-adrenoceptor blockers and use in BPH

Schering-Plough discloses oximes with neurokinin-antagonist activity

Selective, stable and peripherally acting alpha2-adenoceptor agonists patented by P&G

Lead GnRH antagonist presented at Endocrine Society meeting by Abbott, TAP

Thiourea derivatives of plaunotol with good anti-H. pylori and antiulcer activity

Axonyx and NIH collaborate on development of selective BChE inhibitors for use in AD

Sustained-release formulation of GnRH antagonist assessed for PD/PK in dogs

ENDO '99: steroid mimetic agent with selective anabolic effects on osteoblasts from RWJ

Ipamorelin exerts potent GH secretagogue activity in pig fetuses

Higher doses of levetiracetam evaluated for efficacy and, particularly, tolerability in epileptics

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