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BioWorld Science

July 7, 1999

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Group III mGluR agonist produces anticonvulsant and neuroprotective effects

Novel small-molecule macrophage SR-A antagonist described

Trimeris begins phase I trial of second fusion inhibitor

King Pharmaceuticals and Medeva to copromote Altace cardiovascular treatment

LecTec granted patents on cotinine for smoking cessation and psychiatric disorders

Biovation and Tanox enter agreement for antiinflammatory product development

APOE*4 allele increases risk of osteoporotic fractures

Verotoxin eliminates astrocytoma tumors in mouse model

British Biotech announces preliminary results for year ended in April 1999

SmithKline Beecham and Fournier enter agreement for new antithrombotic

Cell Genesys and Mitotix make progress toward a gene therapy product for restenosis

Non-thiol-containing peptidomimetic protein farnesyltransferase inhibitors from Merck

Inhibitors of key enzyme in kynurenine metabolic pathway designed at Pharmacia & Upjohn

Yamanouchi prepares selective inhibitors of Ca2+ release-activated Ca2+ channels (CRACC)

Ad-W9 fusion molecule shows potential in cancer gene therapy

Dual-acting piperazines inhibit TNF-alpha production, stimulate IL-10 production

Avigen's AAV-AADC is a promising gene therapy for Parkinson's disease

New purine PDE4 inhibitors from Mitsubishi useful for asthma Rx

Novel antidepressants from SB act on multiple 5-HT receptor subtypes

ETA antagonist evaluated for antivasoconstrictor effects and protective effects in cold brain trauma

Symposium explores potential of bimoclomol in diabetic complications and other disorders

Antisense therapy: a novel treatment for asthma

Zaditen in the treatment of pediatric respiratory disorders

Apex Bioscience acquired by German biotechnology company

Eptifibatide authorized for marketing in all E.U. member states

New milrinone analogues exhibit superior inotropic activity and high safety

Nexell's stem cell selection systems approved for U.S. marketing

Uroselective alpha-adrenoceptor blocker GYKI-16084 assessed in BPH and spinal cord injury models

Sleep improvements associated with HRT in postmenopausal women

Antiarrhythmic effect of Z-13752A, a dual ACE/NEP inhibitor, is mediated by bradykinin

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