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BioWorld Science

July 12, 1999

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Vancomycin-tolerant S. pneumoniae detected and analyzed

Delta-opioid receptor activation as preconditioning, similar to natural hibernation

Zanamivir shows promise in influenza prevention

Mallinckrodt and SmithKline Beecham sign copromotion agreement for ADHD drug

Patient enrollment completed in study of shortened Targis treatment for BPH

Digital Gene Technologies and Recordati reach milestone in atherosclerosis agreement

Connetics enters licensing and development agreement with Paladin for ConXn

AxyS Pharmaceuticals forms new subsidiary

Company Profile: Maret

BTG acquires novel technology for treatment of HIV

Clinical trials commence for two new Eisai compounds

Allergan ciclosporin NDA up for review this month by advisory committee

New orally bioavailable salt of ET antagonist prepared by SmithKline Beecham

Antitumor and antibacterial compound isolated from cultures of Streptomyces at Kyowa Hakko

Lilly designs selective 5-HT1A antagonists especially for nicotine/tobacco withdrawal

Human Genome Sciences discovery may lead to novel immunotherapies and vaccines

P2X7 receptor antagonists described in recent patent literature

Aromatic hydrazones from Uniroyal with anti-HIV-1 activity encompassing mutant strains

Anti-CD154 antibody facilitates islet allograft survival in highly relevant preclinical model

Potential of cerebrocrast in diabetes suggested by animal data

INO-5042: new agent for venous insufficiency proves effective in various animal models

Orphan Medical, Pierre Fabre sign letter of intent to license Busulfex

CAT gets U.K. approval to begin phase II trials of novel glaucoma treatment

Johns Hopkins team identifies unusually promising new treatment for ALS

E.U.-wide approval obtained for Ziagen

Inhibitors of P. carinii and T. gondii DHFR developed at U.S. universities

Allelix characterizes first-generation NGF receptor antagonist with antiallodynic properties

Rapamune up for FDA advisory committee review in late July

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