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BioWorld Science

July 21, 1999

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Priority review status granted to Immunex's MS drug

Abgenix files IND for ABX-EGF

Use of zonisamide for neurodegenerative disorders

Modulators of cGMP production developed at HMR

Klinge continues to focus on cytostatic/immunosuppressive carboxamides

Amgen reveals latest in inhibitors of matrix metalloproteinases

Novel paclitaxel analogues under evaluation at Bristol-Myers

Collaborative research at HMR and Genentech yields new vitronectin receptor antagonists

Antiherpesvirus agents in the Pharmacia & Upjohn pipeline

Spironolactone-containing drug regimen: the new gold standard for treating heart failure

Novalon and Ares-Serono enter research collaboration

Novartis exercises option to license complement inhibitor from Avant

Progen updates drug development programs

Janssen will copromote Pharmacia & Upjohn's new antidepressant in U.S.

First report of in vivo efficacy of nonthiazolidinedione PPAR-gamma activator

Z-350, a novel treatment for BPH with a dual mechanism of action

Licensing opportunity from NIH: novel and potent antiangiogenic molecule

American Home Products receives approvable letter for GERD therapy

Conformationally constrained putative atypical antipsychotics designed by European group

Structure and physicochemical properties of Metastat published

Wampole launches rapid diagnostic test for Lyme disease

Phase II trial results in colorectal and lung cancers support efficacy and tolerability of S-1

EntreMed signs manufacturing agreement for Angiostatin in preparation for phase I trials

CRP inhibition as a potential new target for lipid-lowering drugs

Archaeosomes with or without coenzyme Q10: biodistribution in mice after i.v., i.p. and p.o. dosing

Targeted doxorubicin chemotherapy for liver cancer tested in phase I trial

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