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BioWorld Science

Dec. 16, 1999

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Lexicon Genetics to provide knockout mice for BASF

Camptosar designated for priority review for new indication

New to the U.K. market: ophthalmic steroid from Alcon causes less IOP elevation

Infliximab now available in U.K. through Centocor licensee

Promising late-stage compounds discussed at Merck & Co. analyst meeting last week

ViroPharma and Wyeth-Ayerst form alliance to develop HCV drugs

Immune Response acquires T-cell receptor technology from Connetics and Xoma

Alliance's NDA for Imagent accepted for FDA review

Vasogen to commence clinical trials of VAS-981 for prevention of GVHD

Centaur comments on NXY-059 development

MGI Pharma commences phase I weekly dosing study with irofulven

Aventis finally becomes a reality

Novel inotropic agent EGIS-9377: potential advantages in the treatment of CHF

AstraZeneca files for new asthma combination product in Sweden

More on PTPase inhibitors in development at AHP

COX-2 inhibitor suggested to be active in squamous cell carcinoma

Antidiabetic thiazolidinediones under study at Taiho

Sordaricin derivatives with useful spectrum antifungal of activity

Pfizer investigates antipruritic activity of 4-phenylpiperidines

2,5-Pyridinedicarboxylic acid derivatives from Dong Wha inhibit retrovirus RT

Banyu tests improved successor to NB-506

SmithKline Beecham seeks approval of Factive in U.S.

Antiplatelet agents synthesized at Chinese university

Novel naturally occurring DNA polymerase beta inhibitor discovered at U. of Virginia

Novartis files NDA for extended-release formulation of fluvastatin

Paclimer Microspheres from Guilford progresses to human studies

Cathepsin C may be an important mediator in the development of periodontitis

Quark and Mitsubishi-Tokyo reach milestone in gene-based drug discovery collaboration

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