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BioWorld Science

Jan. 4, 2000

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Inex makes continued progress in anticancer programs

Company Profile: Angstrom

Pharmacia & Upjohn scientists isolate Alzheimer's-related gene

NEP inhibition with candoxatrilat increases renal response in mild CHF

Calcineurin inhibitor FK-506 prevents cardiac hypertrophy in rats

Chiron prepares highly immunogenic and bactericidal N. meningitidis vaccine

G-CSF mimetics discovered at SB and claimed for neutropenia and infections

Agents for immune or inflammatory disorders from Boehringer Ingelheim

Retinoids with antineoplastic activity designed at Ligand

Merck presents latest discoveries related to treatment of HIV and AIDS

Avanir's new benzimidazole analogues inhibit IgE response to allergens

Miltefosine tested as oral treatment for leishmaniasis

Inspire and UNC describe method of enhancing airways mucus secretion

New nonpeptide compound AY-0068 is a potent, selective and metabolically stable tryptase inhibitor

LY-329146 reverses MRP1- and also P-glycoprotein-associated MDR in cancer cells

Naturally occurring resorcylic acid lactone as potent and selective MEK inhibitor

Total synthesis, structure reported for antifungal antibiotics produced by Penicillium

Tanabe Seiyaku discovers three new 20S proteasome inhibitors produced by actinomycetes

International patent covers new antiangiogenic compounds in development at Abbott

CytoTherapeutics sells Encapsulated Cell Technology to Neurotech

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