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BioWorld Science

Feb. 7, 2000

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Reduced risk of sudden death associated with implantable defibrillators

Restenosis prevention trial of tranilast is largest ever

Phase IIb studies demonstrate anti-HIV activity of (+)-calanolide A

Long-term expression of factor VIII gene achieved in mice

Brazilian approval for Genzyme General's Thyrogen

Ivax and Glaxo Wellcome renegotiate asthma device agreement

Monsanto and Pharmacia & Upjohn outline additional merger details, late-stage products

Second group dosed in early clinical evaluation of Axonyx's phenserine

Palatin Technologies' BLA for LeuTech accepted by FDA for full review

Novel kinase-inhibitory series for AD and cancer presented by Bayer

New antisense oligonucleotides targeting human SMAD3 from Isis

FDA approves tablet formulation of Protonix for erosive esophagitis

Titan establishes collaboration with Schering AG for Parkinson's disease therapy

Major presentation of clinical trial results for BMS protease inhibitor

Taisho discloses new agents for CRF-related diseases

Merck evaluates new anti-HIV combination in phase I trials

Immunomodulating CB2 receptor ligands in development at Sanofi-Synthelabo

Effective and nonirritating beta-diketones and their use for asthma, etc.

Kyowa Hakko presents antitumor agents interacting with farnesyltransferase

Benzoxazoles from Byk Gulden inhibit PDE4 and are particularly useful for asthma Rx

Lymph-targeted antitumor mitomycin C conjugate prepared at Chinese university

Cyclopentanones with antitumor and/or antiinflammatory activity synthesized at Shenyang university

Peloruside A: a cytotoxic macrolide isolated from a marine sponge in New Zealand

Antiinflammatory effects of macrolides investigated in vitro and in vivo

Levaquin as the first antimicrobial for CAP caused by resistant S. pneumoniae

Development of Chlamydia vaccine subject of Argonex/Wyeth-Lederle collaboration

Positive results of capravirine monotherapy and combination therapies in HIV-positive patients

Late-breaking news: Pfizer wins bid for Warner-Lambert

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