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BioWorld Science

March 31, 2000

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Preclinical study shows FGF-4 gene therapy increases cardiac function in setting of heart failure

Phase I/II clinical trial data reported for MTC-DOX in liver cancer

Optison to enter pivotal clinical trials in Japan for second indication

RHeoGene updates gene-switching development program at BIO 2000

AngioMARK shows promise for diagnosis, management of muscular dystrophy

UroGen awarded SBIR grant to support prostate cancer gene therapy product development

Regeneron commences phase II Axokine trial for treatment of obesity

Nortran begins phase II trial of CP1 for chronic idiopathic cough

Safety and tolerability of phenserine confirmed in phase I clinical trial

Breast cancer trial of annamycin commenced by Aronex

Cell Therapeutics submits NDA for arsenic trioxide

Draxis seeks approval of Levulan PDT in Canada

New Toyama compounds useful for influenza virus infections

Pola presents new antifungal products

Diarylbenzopyran derivatives designed at Pacific for inflammation, pain and fever

Recent Japanese patent covers Arax's new antiulcer agents

Orally effective GH secretagogues claimed by Sumitomo

Inhibitors of Lp-PLA2 with pyrimidinone structure claimed by SB for atherosclerosis

Potentially safer antimigraine agents presented at ACS meeting by Canadian company

A-228839: synthesis of a new agent for blocking Ras function

DuPont identifies potent, orally active CRF antagonist

Health Canada approves Avandia for treatment of type II diabetes

Meperidine analogues under study as dopamine uptake inhibitors by NIDA and collaborators

European Commission approves Monsanto/Pharmacia & Upjohn merger

Multiple mechanisms of action proposed for beneficial cardiac effects of HNS-32

K(ATP) channel opener YM-934 protects cardiac mitochondrial and functional activity during ischemia

Natural and synthetic neurotrophic factor secretion enhancers under study in Japan

Cardioprotective effects of TAK-044 in isolated perfused rat hearts

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