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BioWorld Science

April 3, 2000

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Avant reports preliminary results from phase I/II infant TP-10 study

Avax begins phase II study of M-Vax in stage IV metastatic melanoma

Phase III study of ETEC vaccine does not meet primary clinical endpoint

Vion and the NCI to commence phase I trial of TAPET for advanced cancer patients

Neurocrine Biosciences awarded NIH grant for retinal ischemia research

Tostrex enters phase III trial for Rx of male hypogonadism

QLT and Ciba Vision report positive Visudyne clinical results

Hemosol completes pivotal phase III trial of Hemolink in CABG patients

NeoTherapeutics commences worldwide clinical trial of Neotrofin as Alzheimer's treatment

Aptosyn clinical trial completes enrollment in children with FAP

deCODE Genetics successfully maps stroke gene

Immune Response to develop potential preventive HIV vaccine

New series of gastric acid pump inhibitors in early research at AstraZeneca

Sodium channel blockers useful as anticonvulsants in development at Glaxo Wellcome

AstraZeneca presents new pyrimidine-based cyclin-dependent kinase inhibitors

Novel antiplatelet agents in the Searle pipeline

COX-2-inhibitory indole compounds synthesized by Pfizer

Large group of GH secretagogues disclosed in recent patent by Lilly

AACR news: ABT-627 inhibits ovarian carcinoma growth and angiogenesis

United Therapeutics to develop novel antiviral agents

New study will assess safety of Maxamine-containing triple drug therapy in HCV

BMS-275291 inhibits angiogenesis and/or tumor metastasis in vivo and in early clinical trial

Merger of Monsanto and P&U completed; Pharmacia begins trading

Pharmacokinetics, toxicity, biological activity of COL-3 in cancer patients

Novel anticoagulant presented by Ajinomoto at Japanese Pharmacological Society meeting

Binding and neuroprotective studies with SM-31900 indicate potential in epilepsy, cerebral ischemia

AACR highlights: selective PDGF receptor antagonist effectively reduces tumor growth in vivo

Apoptosis induced in human leukemia cells by topoisomerase I inhibitor BN-80915

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