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BioWorld Science

April 19, 2000

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In vitro and in vivo activity of novel 1beta-methylcarbapenem

Genetronics expands electroporation collaborations for gene therapy

CEP-4143, a new calpain antagonist, affords neuroprotection in rats with traumatic SCI

Genset and Sanofi-Synthelabo enter CNS-related pharmacogenomics collaboration

Paladin's pipeline matures

Polyethers from Fujisawa exert broad-spectrum antiinfective activity

Cytoclonal develops c-RAF1 oncogene inhibitor

Faulding obtains Australian rights to ConXn

NicOx makes significant progress during 1999

Matrix's IntraDose receives orphan drug status

NeoTherapeutics moves Neotrofin closer to regulatory approval during 1999

CPMP recommends European approval of Visudyne for wet AMD

Genta's lead antisense drug reduces human Merkel cell tumors in mice

The Liposome Company to hold special stockholders meeting in May regarding merger with Elan

Taxol approved in Canada for adjuvant treatment of breast cancer

Sanofi-Synthelabo presents alpha-adrenoceptor ligands for incontinence, venous insufficiency, etc.

Cannabinoid receptor antagonists from Aventis described for CNS and other conditions

Putative GABA mimetics designed by Warner-Lambert

Human chorionic gonadotropin vaccines for interrupting fertility

Warner-Lambert describes potent new anti-HIV agents with improved pharmacokinetics

Compounds inhibiting the MDM2-p53 interaction in development by AstraZeneca

Nitro derivative of prednisolone, presented this week, possesses superior antiinflammatory activity

Long-term treatment with daily pegvisomant proves safe and effective as acromegaly Rx

Diacrin puts phase I stroke trial on hold

Artemisinin analogue synthesized and evaluated in vitro for antimalarial activity

Anilide MTP inhibitors presented at Pharmaceutical Society of Japan meeting

Identification of potent and selective PDE5 inhibitor discussed at Pharmaceutical Society meeting

Two abstracts document antimycobacterial activity of new benzoxazinorifamycin

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