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BioWorld Science

May 25, 2000

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Array BioPharma and Tularik join forces in creating small molecule library

Therapeutic and marketing potential expand for Cystistat

Cell Genesys reports encouraging preclinical data for leukemia vaccine

Molecular mechanism of atherosclerosis discovered

Hyseq extends cancer gene discovery agreement with Chiron

Isotechnika's new immunosuppressive drug successfully completes phase Ia

Allergan to collaborate on developing neurotoxin-based analgesics

Amylin plans Symlin NDA submission by end of 2000

Cell Therapeutics receives priority review for ATO during Q1 2000

Aronex updates Atragen and Nyotran clinical progress at annual meeting

Novel NO steroid derivative reduces colon inflammation in mice

Proteasome inhibitor MG-132 endowed with antineoplastic activity

Chiron's Fluad influenza vaccine approved under E.U. mutual recognition procedure

GTI-2040 phase I/II trial on target for completion by year-end

TNP-470 delays gastric ulcer healing in rats

Darbufelone shows better GI safety profile than naproxen in clinical study

DDW news: ALX-0600 has intestinotropic properties in rodents

Bosentan reduces leukocyte-endothelial adhesion in rat model of IBD

KS Biomedix provides final phase II results of CBF-BS2 in rheumatoid arthritis

Novel TNF inhibitor effective in two models of IBD

VPA-985 useful in hyponatremia

Oregon State U. researchers disclose curacin A derivatives with improved stability

New P&G compounds claimed for cardiovascular and other disorders

AstraZeneca develops new treatments for cancer, rheumatoid arthritis, etc.

Compounds blocking ICAM-1 activity described by Roche

Recent patent covers new quinolone antibacterial agents synthesized at SB

Lipophilic camptothecin derivatives with favorable profile of activity, toxicity

Lilly prepares potent and orally active thrombin inhibitors

ASCO news: polymeric CPT derivative assessed in phase I for toxicity and pharmacokinetics

Phase I data presented at ASCO for L-377202, a peptide conjugate of doxorubicin

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