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BioWorld Science

May 24, 2000

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NCI signs CRADA with Exelixis

Ligand updates product development programs

Novo Nordisk highlights Q1 developments

Titan to have five efficacy studies in progress this year for MAb products

Company Profile: Microbiotix

Epimmune and Pharmacia report data on promising cancer vaccine

PulmoSphere improves drug delivery to deep lung

IL-10 mediates Vasogen's immune modulation therapies

GelTex toxin-binding compound offers promise in C. difficile colitis

Cubist seeks to expand daptomycin companion study; positive results presented in endocarditis model

Compounds from the NONOate class hold promise in the treatment of pulmonary hypertension

Orally active ICAM-1/E-selectin inhibitor effective against colitis in rhesus monkeys

News from DDW: NO derivative of URSO protects against liver damage in mice

Early use of PDT with verteporfin in age-related macular degeneration

Adolor patents use of peripherally acting opiates for pruritus

Antioxidants from ADIR especially active on the CNS

Marine sponges yield new biologically active discorhabdin compounds

DuPont prepares fibrinogen antagonists useful for imaging thrombi

Proteasome inhibitors and their use presented by Max Planck

New quinolones useful as antiinfective monotherapy or in combination

Inhibitors of cyclin-dependent kinases claimed by DuPont for cancer

Oral rCT-B shows preclinical activity against colitis

Metabotropic glutamate receptor agonists and their use disclosed by Taisho

DDW presentations support efficacy of exisulind in FAP and related conditions

Recent data on new IBS treatment tegaserod presented at Digestive Disease Week

Merck & Co. and Schering-Plough to jointly develop new combination products

Pfizer/Warner-Lambert merger cleared by European Commission

Amitriptyline demonstrates potential for use in IBS at low doses