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BioWorld Science

June 30, 2000

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Process of neurodegeneration linked to calpain activation

Receptor linked to sensitivity to inflammatory pain

FDA approves first drug to treat growth failure in children with Prader-Willi syndrome

NitroMed patents series of nitrosated or nitrosylated H2 antagonists

Cel-Sci receives permission to start phase II cancer trial in Canada

FDA approves Bayer's next-generation hemophilia A treatment

Tripos and Lipha to collaborate on drug discovery for metabolic and associated diseases

DuPont selects DPC-423 for clinical evaluation as an orally active anticoagulant

AWD-12-343 compares favorably with known PDE4 inhibitors in model of lung inflammation

Two new EP1 receptor antagonists under development at Ono for pain and cancer

Experimental study suggests potential of CP-0597 in the management of spinal cord injury

New market launch for Azopt

E.U. approves Remicade for rheumatoid arthritis

May launch announced for UCB H2 receptor antagonist

Late-stage anxiolytic candidate dropped from Welfide development pipeline

Axokine phase I results reported at ENDO 2000 meeting

Peptide Therapeutics reports positive phase III results for yellow fever vaccine

Enrollment in phase III trial of sepsis treatment stopped by Lilly

IGFAM: new members of the human immunoglobulin superfamily discovered by Incyte

Identification and potential uses of new RING finger protein revealed

New iNOS inhibitors claimed by AstraZeneca for use in inflammation and pain

U.K. scientists present new agents with vasodilating and antiplatelet properties

Cathepsin K inhibitors designed at SB for bone and cartilage disorders

Novel diagnostic test for tuberculosis with advantages over current tests

Antimicrobial and immunostimulating heterocycles synthesized at Natural Drug Sciences

Novel Vernalis compounds combine antioxidant and iron-chelating activity

FDA approves Targretin gel for treatment of cutaneous T-cell lymphoma

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