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BioWorld Science

July 3, 2000

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Tumor growth and spread blocked by inhibition of RAGE-amphoterin interaction

Comparison of flutamide and finasteride in the treatment of hirsutism

Kinase inhibitor PKC-412 exhibits both antiproliferative and antiangiogenic properties

Micrologix Biotech successfully completes phase I clinical trial for acne treatment

UT to develop, commercialize sustained-release beraprost in North America

First report of a selective, small-molecule FSH receptor antagonist at ENDO 2000

Buccal tablet formulation of testosterone suitable for HRT in males

Cell Therapeutics establishes new subsidiary

New inhibitor of Abeta production emerges from collaborative Scios-DuPont research

Potential new opioid analgesics designed by AstraZeneca

Kyowa Hakko initiates phase I testing of treatment for urinary incontinence

Novel alkaloids isolated from Daphniphyllum exert cytotoxic effects against cancer cells

Small molecule from Novartis is a specific inhibitor of cdk4 kinase

Anti-HCMV 8-hydroxyquinoline-7-carboxamides described at recent medicinal chemistry meeting

Additional benefit described for statins in large case-control analysis: reduced fracture risk

Preliminary data indicate potential of NPS-1776 as therapy for neurological disorders

ZymoGenetics identifies and characterizes novel lipocalin protein with antimicrobial properties

Anti-RHAMM monoclonal antibodies useful for proliferative diseases

Schering AG patents fluorinated compounds that inhibit NOS

Novel caprolactam antitumor agents under study at Novartis

Merck reports discovery of class of inverse agonists at the GABA-A alpha5 receptor subtype

New protein farnesyltransferase inhibitors in early development at Pfizer

Two recently issued patents describe new fibrinogen receptor antagonists designed at DuPont

H. pylori antigenic protein for use in vaccines

Compounds with utility for the treatment of cytokine-mediated disorders

Ajinomoto forges ahead with pipeline products

Organon launches new estrogen-free oral contraceptive pill in Europe

CPMP recommends approval of Caelyx for treatment of advanced ovarian cancer

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