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BioWorld - Monday, May 6, 2024
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BioWorld Science
Sep. 7, 2000
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Ibuprofen as effective as indomethacin in treating patent ductus arteriosus
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Diltiazem and diuretic + beta-blocker display equal efficacy in hypertension trial
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Ditropan XL and Detrol produce similar incidence of dry mouth
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Novel approach to identifying therapeutic targets and high-affinity ligands/substrates
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Discovery of potent alphavbeta3 antagonists described by Merck at ACS meeting
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New phosphodiester analogue synthesized at Duke
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New substituted indolealkanoic acids are potent and selective aldose reductase inhibitors
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DuPont designs potent and selective factor Xa inhibitors with excellent PK profile
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ACS presentation details chemistry, SAR and pharmacology of CV-1013
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Elan/Wyeth-Ayerst describe SAR on series of small-molecule VLA-4/VCAM-1 inhibitors
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Inhaled prostanoids + PDE inhibitors for improving therapy of pulmonary hypertension
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Use of AII receptor antagonists in prevention, treatment of AMI
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FDA approves ciprofloxacin for treatment of postexposure inhalational anthrax
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Pharmacia's Aromasin receives clearance from Health Canada
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Flavopiridol, a known antitumor agent, now reported effective in models of vascular injury
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New JT compounds exert immunostimulating, antiviral and antitumor activity
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Meiji Seika describes inhibitors of PARP and their use in recent patent
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Compositions for pathologies associated with insulin resistance claimed by Merck KGaA
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Teijin reports on new class of factor Xa inhibitors
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New cinnamamide derivatives and their use described by Tsumura
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Nonpeptide agonists of GLP-1 receptor presented by Novo Nordisk and Agouron
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Thrombin inhibitors and their prodrugs synthesized at AstraZeneca
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New heterocyclic CCR5 antagonists from Merck as leads for effective anti-HIV agents
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Bone Care launches Hectorol Injection
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Lundbeck and Mitsui establish citalopram collaboration agreement
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Cantab finalizes DISC-HSV agreement with Glaxo Wellcome
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Acquisition of Spiros by Dura now complete
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