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BioWorld Science

Sep. 12, 2000

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NK1 receptor antagonist may be useful for treatment of chronic pain

Transgenic pig cells restore impulse conduction in injured rat spinal cord

Efficacy of Org-31540/SR-90107 demonstrated in four phase III studies

Small-molecule antioxidant patent granted

Studies reveal association between hypocretin deficiency and narcolepsy

StressGen commences phase II trial of HspE7 for treatment of cervical cancer

Novopharm Biotech changes name

Aquila awarded grant to develop vaccines against S. aureus

ImmunoGen and Abgenix form multiproduct collaboration

Novel mechanism of SB-220453, a new antimigraine agent, studied in cats

Bayer identifies potent, orally active phenyl pyrazolyl urea p38 kinase inhibitors

Antiproliferative Ca2+ channel blockers and SAR reported by U. Virginia

New taxoid RPR-109881A evaluated in phase I trial in patients with solid tumors

New PLA2 inhibitor protects liver against I/R injury in canine model

CGRP antagonists as a novel approach to the treatment of migraine

ISAtx-247 as a potentially improved alternative to ciclosporin

Possible protective role for ECT inhibitor in hepatic I/R injury outlined at recent congress

Immunosuppressive effects of new peptide confirmed; additional hypolipidemic effects seen

Anticonvulsant glutamate receptor blockers in the Pfizer pipeline

Arch scientists discover new peptides with mitogenic properties

Novel beta-lactamase inhibitor from American Cyanamid synergistic with piperacillin

Benzimidazoles useful as GH mimetics claimed by former P&U

Cariporide may improve the preservation of NHBD organs

French institutes join forces to design pseudopeptide MMP inhibitors

Closing of SB/GW merger delayed until end of the year

Synthesis and use of new heterocyclic antiinflammatory agents described by Boehringer Ingelheim

Novel inhibitors of tyrosine kinase from Merck useful for angiogenesis-related disorders

Kyowa Hakko reports new series of proteasome inhibitors

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