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BioWorld Science

Aug. 30, 2000

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Inspire reports synthesis of more stable P2Y2 agonists

Stem cell transplantation induces remission in persistent SLE

Testing reveals lurtotecan is less active than its low-clearance formulation

Cancer vaccine shows potential for decreasing risk of relapse and death

Low-dose transdermal testosterone tested in chronic stable angina

Bayer's MTP inhibitor assessed preclinically

Dual ETA/ETB antagonist provides hemodynamic benefits in CHF

Selective dopamine agonist provides antiarrhythmic benefits in chronic heart failure

Schering AG's Yasmin receives European-wide approval

Safety and efficacy data reported on AstraZeneca's P2T receptor antagonist in PTCA

Watson completes acquisition of Schein

Ezetimibe inhibits cholesterol absorption; tissue localization explored

Roxifiban inhibits platelet aggregation dose-dependently in CAD patients

AstraZeneca's rosuvastatin causes rapid reductions in LDL cholesterol

LU-135252 normalizes pulmonary arterial pressure and blood pressure in two experimental models

Lilly reports synthesis of novel mGlu2/3 agonists and antagonists

Novartis updates transplantation pipeline at ongoing congress

Tablet form of Rapamune receives FDA approval

Herceptin approved in E.U. for treatment of HER2-positive metastatic breast cancer

Matrix metalloproteinase inhibitors claimed by Aventis

SmithKline Beecham reports compounds useful for treating cytokine-mediated disorders

Neurogen discloses new series of compounds interacting with dopamine D4 receptors

Merck & Co. claims compounds useful for treating cognition disorders

Pharmacia presents new antiviral agents

HIV integrase inhibitors disclosed by Shionogi

Viral protein products reduce transplant rejection in preclinical study

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