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BioWorld Science

Sep. 14, 2000

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Medarex and Oxford GlycoSciences to codevelop human antibody therapeutics

GlycoDesign and Seikagaku expand drug development agreement

Safety study of anti-hepatitis C ribozyme compound completed

Oxygent reduces the need for donor blood in phase III trial

Synthetic antioxidant compounds extend the life span of C. elegans

St. John's wort extract and imipramine equally efficacious in treating depression

Telomerase immunization induces antitumor response

Nebulized heparin reduces airways inflammation, improves spirometric parameters in asthma

German scientists study antisense oligonucleotides as a novel, noninvasive approach to asthma

Renal I/R injury prevented by VAS-971 therapy in canine model

HuM291 appears to induce transplant tolerance via apoptosis of activated T-cells

New leads in the search for next-generation microtubule-directed taxoids

Clinical candidate for allergic cutaneous disorders selected at Japan Energy

Cystistat approved for expanded indications in Europe

Analgesic activity demonstrated for Abbott's novel nAChR ligands

Vernalis patents new NMDA antagonists with favorable cortical to cerebellar ratio

Recent patent covers heterocyclic 5-HT reuptake inhibitors discovered at BMS

Potential new anticonvulsants presented by Boehringer Ingelheim

Screening collaboration between CDD and CST to identify novel kinase inhibitors

Clinical trials with polymer platinate AP-5280 to begin

Inhibitors of nitric oxide synthase in early development at Pharmacia

Exclusive access to technology for potential cancer vaccine granted to Viragen

Nanomolar binding affinity for A3 receptor demonstrated for certain new thiazolopyrimidines

British Biotech designs new LTA4 hydrolase inhibitors

Prodrugs of known BK(Ca) channel opener reported by BMS

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