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BioWorld Science

Oct. 2, 2000

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Northwest's prostate cancer vaccine shows favorable progress in clinical trial

Endo meets with FDA to clarify requirements for MorphiDex approval

FDA completes review of supplemental BLA for Rituxan

Salus receives NIH grant to aid in development of anti-HIV treatment

Angiogenic activity suggests broadened role for statins

Hollis-Eden cleared to commence further HIV clinical trials in South Africa

Interferon beta delays development of multiple sclerosis in high-risk subjects

SBIR grant awarded to Imgenex to develop monoclonal antibodies for osteoporosis

Newly synthesized selective AMPA agonist used to elucidate receptor function

Acidic quinolones with potent antibacterial activity identified at Wakunaga

Servier investigates synergistic interaction between alpha2 blockade and monoamine uptake inhibition

Sigma-Tau selects new camptothecin derivative for preclinical development

Potent adenosine transporter inhibitors synthesized by Kyowa Hakko useful as tools and leads

FDA approves Mifeprex for termination of early pregnancy

New approach to oncolytic, skin disorders based on specific inhibition of 4-hydroxylase

First oral drug for rare neurodegenerative disease launched in Japan

Selective COX-2 inhibitor with promising profile emerges from Abbott R&D

Efficacy in experimental IBD demonstrated for immunosteroid recently acquired by Hollis-Eden

Two new patents cover VCAM-1/VLA-4 inhibitors from Roche and their use

Beacon describes preparation and activity of improved butyric acid esters

Meiosis-regulating cholestane compounds designed by Schering

Newly isolated antibiotic characterized at Pola as having antifungal and antibacterial activity

Chugai examines novel enzyme inhibitors as potential anticancer agents

Migration-inhibitory peptides identified and investigated at Kyowa Hakko

New vitamin D compounds for bone disorders prepared at Sumitomo

Taiho describes new series for use in reducing elevated ammonia levels

Bosentan begins FDA approval process for pulmonary hypertension

Ligand's lasofoxifene enters phase III for osteoporosis, triggering milestone payment

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