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BioWorld Science

Oct. 3, 2000

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Bristol-Myers Squibb and Lexicon team up for high-throughput genetic target validation

Telik awarded SBIR grant for new TRAP applications

MGI Pharma commences phase II liver cancer trial with irofulven

NIH grants anti-Notch-1 monoclonal antibody technology to Viragen

SangStat receives grant to fund studies of RDP-58 in primate model of HIV infection

Alkermes completes patient enrollment in clinical trial of new treatment for alcoholism

Antex Pharma and Lyotropic create joint antibiotic development program

Pfizer transfers anticancer compound to OSI; early trial results released

Rigel obtains rights to antiviral drug technologies from Questcor

Inhaled morphine in phase II for breakthrough pain

Thymitaq enters phase III for HCC

First approval for recombinant drug for infertility

Spanish group presents new CCK1 antagonists with anxiolytic-like effects in Alicante

Versicor identifies promising leads in new class of antibiotics: inhibitors of peptide deformylase

New class of oral TNF-alpha synthesis inhibitors presented at September conference

Dana-Farber reports SAR profile of novel class of antifolates

Novartis reports success in developing orally active dual MMP/TNF-alpha inhibitors

Keppra receives E.U. approval for treatment of epilepsy

Dual D2/beta2-adrenoceptor agonists in clinical development at AstraZeneca for respiratory diseases

FDA approves Fosamax for use in men with osteoporosis

Clinical safety and pharmacokinetics of ravuconazole discussed at ICAAC

Novel polypeptide with potential for diabetes Rx described by ZymoGenetics

Angiopoietin-related protein isolated at Regeneron

New benzaldehyde derivatives from Norsk Hydro suppress increased cell proliferation

Synthesis and use of new Sankyo compounds elevating [Ca2+]i levels described in recent patent

Anti-H. pylori agents prepared and tested at Welfide

Mevinolin derivatives for disorders mediated by LFA-1/ICAM-1 interactions

GGTase-inhibiting antifungal agents identified by Banyu

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