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BioWorld Science

March 12, 2001

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NIH licensing opportunity: ribonuclease H1

Avant Immunotherapeutics updates development programs

Neurocrine announces encouraging phase I data for CRF1 antagonist

Regulation of Cyr61 gene expression and cell migration or chemotaxis

Inhibitex initiates phase II trial of therapy for life-threatening staphylococcal infections

Protegrin IB-367 shows antimicrobial activity, good safety in phase IIa for prevention of VAP

TranXenoGen and Abbott establish collaboration for monoclonal antibody production

Genmab reports encouraging results with HuMax-CD4 for RA

ACE inhibitor lisinopril effective in prophylactic therapy of migraine

NCX-4016 reduces restenosis in hypercholesterolemic mice

Treatments for Huntington's disease and related disorders sought by Cogent and Elan

Protarga begins phase II trial of Taxoprexin DHA-paclitaxel

Ezetimibe can be safely administered to adolescents and in combination with a number of drugs

Trials begin with human protein for the prevention of chronic lung disease in premature babies

Analogues of BD-1008 possess functional sigma receptor antagonism and anticocaine effects

Targacept and Dr. Falk to develop novel ulcerative colitis therapy

Texas Biotechnology summarizes major achievements over past year

Proof-of-principle clinical study begins for P-57 as obesity treatment

Bilobalide-derived NV-31 appears to promote neuronal survival via antioxidant effect

YC-1 may prevent development of tolerance to organic nitrate therapy

Recombinant human C1 inhibitor enters trials for hereditary angioedema

Methods of treating and diagnosing lysosomal storage diseases

New series of bradykinin receptor antagonists designed by Pharmacopeia

Pseudomycin-related antifungal agents under study at Lilly

Recent patent describes metabolite of MDL-100907 and its use in schizophrenia, anxiety, etc.

Heterobicyclic inhibitors of factor Xa synthesized at DuPont as potential new anticoagulants

Analgesic compounds claimed in international patent by Gruenenthal

Fujisawa claims cGMP-PDE inhibitors particularly useful for erectile dysfunction Rx

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