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BioWorld Science

June 12, 2001

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Aastrom Biosciences and Neoprobe to develop cell therapy for the treatment of cancer

Celgene secures exclusive worldwide licenses to major class of drug target

New data prove Fabrazyme's ability to clear GL-3 from wide range of cell types

Ranolazine improves LV function in heart failure by optimizing myocardial efficiency

Amelioration of RV hypertrophy by endothelin antagonist related to normalization of calcium handling

Dendreon expands phase III trials of Provenge for prostate cancer

Once-daily Ditropan XL receives clearance in Canada

Worldwide rights to Oncolym revert to Peregrine

The Medicines Company provides update on Angiomax clinical trials

Gene therapy as alternative to transplantation in hereditary dilated cardiomyopathy

Treatment of first patients with GTI-2501 begins at University of Chicago Medical Center

TP-508 increases expression of regulatory factors in bone healing

Medarex and Sangamo enter alliance for development of therapeutic antibodies

LJP expands phase III lupus trial to Europe

FDA approves revised labeling for Integrilin

Extension of pemtumomab phase III trial announced following meeting with FDA

Update on development of NeuroSearch/GlaxoSmithKline antidepressant

Hepatoma-specific oncolytic adenovirus CV-890 exclusively kills cancer cells

Biological synovectomy using Granzyme B gene therapy

Androgen receptor modulators designed by Kaken

Otsuka presents new series with potent and selective affinity for adenosine A3 receptors

Diarylamides from Japan Energy inhibit PDGF-induced cell proliferation

Peripheral analgesics targeting the MOP receptor in development at SSP

Inhibition of bone resorption in vitro and in vivo reported for alphavbeta3 integrin antagonist

New inhibitors of protein farnesyltransferase under study as potential anticancer agents

U.S. patent covers cysteine protease inhibitors identified at Naeja

Otsuka scientists identify new inhibitors of collagen production

Novel compounds for neurodegenerative diseases presented by Japanese lab

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