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BioWorld Science

July 12, 2001

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SciClone's Zadaxin receives expanded approval in Mexico

Gene synthesis patent licensed by Blue Heron

S-34211: an orally available direct thrombin inhibitor with potent antithrombotic properties

Safe and effective heparin/LMWH antidote developed at Commonwealth Biotechnologies

P2T antagonist AR-C69931 acts synergistically with PGE1 to inhibit Ca2+ mobilization in platelets

ML-3000 inhibits PMN/platelet interactions in vitro

Factor VIII retroviral construct safe and potentially effective in hemophilia A patients

Blood outgrowth endothelial cell-based gene therapy for hemophilia tested in mice

Human factor VIII-expressing gutless adenovirus vector for hemophilia A

Genencor and Epimmune to codevelop vaccines for three oncogenic viruses

Company Profile: Diabetogen

Beneficial effects reported for T-588 in animal model of ALS

NDS filed for d-methylphenidate in Canada for ADD and ADHD

Immtech International achieves several milestones during fourth quarter

TheraCIM h-R3 enters phase I/II for additional indication

Selective iNOS inhibitor Ono-1714 ameliorates pancreatitis

Peripheral-type cannabinoid receptor ligand shows efficacy in acute pancreatitis

Oral thrombin inhibitors designed at Knoll (Abbott) inhibit both free and fibrin-bound thrombin

OrthoLogic extends Chrysalin license

Combined PDE3/PDE4 inhibitor therapy for obesity

Bezafibrate: the first oral agent with antiinflammatory and antiviral activity in HCV

Allergan claims new cyclopentane derivatives for glaucoma management

CRF antagonists and their therapeutic application reported by Pfizer

Joint research at Japanese labs leads to new series of sphingomyelinase inhibitors

Pharmacological profile of new NK1 receptor antagonist from Roche

Potent GABA-A agonists identified by Merck in a series of pyrazolotriazines

GABA-A receptor ligands useful for anxiety, convulsions described by Merck

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