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BioWorld Science

Oct. 15, 2001

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Serono confirms submission of Rebif amendment to FDA

Bausch & Lomb acquires loteprednol etabonate line

FDA issues approvable letter for UroXatral

CAT and Merck & Co. form HIV alliance

Maxygen brings two new therapeutics into preclinical pipeline

Roche's PEGASYS introduced in first market

Inhibition of p38 MAPK in experimental model of colitis has dual effect

Efficacy of MAP kinase blocker CNI-1493 in Crohn's disease seen in pilot trial

Gene therapy with IL-10 produces therapeutic benefit in experimental colitis

Matrix to initiate new study of tezacitabine in AML

High-dose ISIS-2302 enemas improve symptoms in ulcerative colitis

Favorable OvaRex/chemotherapy clinical trial results in relapsed ovarian cancer reported by AltaRex

First clinical data for new propofol prodrug presented at ASA meeting

GlycoDesign and Leo move new antithrombotics into clinical trials

Cardioprotective effects of landiolol and propranolol compared in guinea pig hearts

MGI Pharma expands phase II irofulven clinical trial in ovarian cancer

Potential new therapeutic target for endotoxin shock: anandamide

Cardioprotective and vasodilating effects described for JTV-519 at ASA meeting

Peregrine's Cotara receives FDA fast track review status

FDA issues approvable letter for Symlin in type 1 and type 2 diabetes

New clinical data show Multikine's ability to eliminate HPV-induced cervical dysplasia

Neuroprotective aminoadamantane derivatives disclosed by Panorama

New VLA-4 antagonists in the Kaken pipeline

Selective dopamine D3 receptor antagonists identified by Pharmacia

Two Japanese patents cover Otsuka's new hypoglycemic/hypolipidemic compounds

Inhibitors of CDKs useful as anticancer agents

Antitumor antibiotics discovered at MCRF in Streptomyces

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