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BioWorld Science

Nov. 21, 2001

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PN-401, an oral uridine prodrug, exerts robust neuroprotection in two animal models

Phase II trial initiated for HspE7 in pediatric recurrent respiratory papillomatosis

Azign Bioscience and Nordic Bioscience to research treatments for bone and joint diseases

Genzyme Molecular Oncology and Kirin Brewery form human monoclonal antibodies collaboration

Approval granted for Actonel in treatment of glucocorticoid-induced osteoporosis

First injectable COX-2 inhibitor Dynastat closer to launch following positive CPMP recommendation

Negotiations begin between Durect and Janssen over marketing rights for Chronogesic

International expansion of Celgene's Thalomid accelerated through recent agreements

Promising candidate for HBV profiled at AASLD meeting

First successful demonstration of Sosei's drug reprofiling approach: DRP-001 enters phase I for UI

VX-497 + interferon alfa safe in HCV patients; trend for enhanced antiviral efficacy seen

Pralnacasan demonstrates preclinical potential as an anticytokine arthritis therapeutic

Gliatech highlights Q3 developments

NeoTherapeutics continues to accomplish milestone objectives

Inhibition of adenosine A2A receptor as novel approach to reducing dermal fibrosis

Pilot trial demonstrates safety, lack of immunogenicity, local antiinflammatory effects for r-hTBP-1

Positive opinion issued for Lumigan by CPMP

Pfizer updates prescribing instructions for Vibramycin to include anthrax inhalation indication

Angiotech extends study of micellar paclitaxel as treatment of severe psoriasis

Multiple doses of humanized anti-IL-6 antibody safe and therapeutically beneficial in RA

NIH awards grant for MetaPhore's research into superoxide dismutase mimetics

PI-88 may have use in the treatment of leukemia

AIT-034 compared to oxiracetam for effects on memory and behavior in mice

Highly potent and selective muscarinic M2 antagonist improves cognition in animal models

New ADIR compounds particularly useful in anxiety

Inhibitors of gamma-secretase claimed by Merck for use in Alzheimer's disease

Japanese patent covers erythromycin derivatives with antibacterial activity designed at Shionogi

Inhibitors of MMPs, TNF-alpha and/or aggrecanase identified at DuPont

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