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BioWorld Science

Feb. 26, 2002

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Nucleoside analogue in phase I/II trials retains good activity against resistant HIV variants

G250 peptide-based vaccines under investigation for renal cell carcinoma

AlloDerm used to regenerate bladder tissue in rats

Data from three clinical studies suggest dutasteride may be the treatment of choice for BPH

Oral prodrug of tenofovir selectively activated in cells and distributed to lymphatic tissues

Clinical data support further study of TMC-125 as monotherapy and in combination

Approval of Tracleer for PAH recommended by European authorities

Early clinical and preclinical data on Sch-C presented in Seattle

European approval of memantine for Alzheimer's disease recommended

EluSys initiates phase I trial of ETI-104

InSite Vision updates progress

Tularik reports clinical progress in 2001 and outlook for 2002

FDA approves Zometa for bone metastases from solid tumors and multiple myeloma

First European approval for Concerta XL in ADHD

ABC(2) and Genentech collaborate in brain cancer

Cypress initiates phase II program for milnacipran in fibromyalgia syndrome

CytRx receives milestone from Merck for TranzFect technology

Paradigm Genetics and Duke sign metabolomics research agreement

NM-3 potentiates effects of chemotherapeutic agents via inhibition of tumor angiogenesis

Takeda discloses antagonists of urotensin-II receptor

Acylsulfonamide compounds with hypoglycemic activity disclosed by Ajinomoto

Glutamate antagonists with potential as neuroprotective agents

Chugai identifies steroid derivatives with antiandrogenic activity

Novel series claimed to be useful in Alzheimer's disease and other Abeta-mediated disorders

Pyrrole derivatives described for treatment of CNS disorders

Roche claims sulfonylpyrrolidine derivatives as metabotropic glutamate receptor agonists

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