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BioWorld Science

April 16, 2002

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Sprinkle administration approved for ADHD treatment

Vioxx labeling changes and new indication

Phase IIA trial of oral AOD-9604 scheduled to begin next month

Preclinical development of PRE-703 for anxiety expected to be completed this year

Hedgehog antagonist with potential in BCC identified at Curis using novel screening assays

Over 95% of prostate cancer patients express target of Provenge vaccine

Squalamine effective in breast cancer model alone and in combination with Herceptin

Potential of Erbitux as combination therapy in colorectal carcinoma

AACR news: Javelin-based vaccine safe and immunogenic in melanoma patients

Spotlight on neuroprotective agents discussed at the AAN meeting

The use of statins in neurological complications

SSADH deficiency, a potentially treatable neurometabolic disease

American Psychiatric Association issues new guidelines on bipolar disorder treatment

AVP antagonists, their SAR and biological activity described by R.W. Johnson at ACS meeting

Protopic launched in Germany for atopic dermatitis

Roche adds MV-026048 to HIV portfolio

Product R to enter phase II as topical treatment for genital warts

Committee recommends approval of Cozaar to delay renal disease in type 2 diabetics

AMD-3100 evaluated in healthy volunteers in combination with Neupogen

Merckle and Forest reach agreement over ML-3000 in U.S.

Dose-titration study of Symlin initiated in response to FDA approvable letter

Basilea patents new antibacterial erythromycin analogues

New compounds from Merck possess 5-HT1A receptor-agonist and D2 receptor-antagonist effects

SSRIs discovered at Pfizer claimed specifically for premature ejaculation

Anticoagulants acting via inhibition of thrombin designed at AstraZeneca

Synthesis and use of factor Xa inhibitors described in patent by Lilly

Selective PPARdelta activators and their use

Indole derivatives bind to D4 receptors and are potentially useful for Rx of CNS disorders

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