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BioWorld Science

April 25, 2002

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SGN-15 and gemcitabine show synergy in vitro in ovarian cancer cells

Zadaxin leads to bone marrow recovery after chemotherapy

Bayer seeks exclusive licensee for progestin agonist

Pretreatment with superoxide dismutase mimetic protects against focal cerebral ischemia in rats

MorphoSys details change in strategy, describes first proprietary therapeutic antibody candidates

Interferon omega safe and effective in HCV-infected patients

LY-582563/MCC-478 more active than PMEA against wild-type and mutant HBV

Histone deacetylase inhibitors in the spotlight at recent meetings

New data on JTT-705 presented at Sapporo meeting

Improved cardiac function following treatment with JTV-519 in heart failure

Nonsteroidal inhibitor of 17-alpha-hydroxylase/17,20 lyase with potential in prostate cancer

Apomate useful for early prediction of response to chemotherapy

Genasense potentiates activity of anticancer agents, retains activity against resistant leukemia

Preliminary results of UK-279276 do not warrant further development in stroke

European orphan drug designation for DTI-015 in malignant brain tumors

AIDSVAX trials clear safety review

AxCell and University of Muenster to research protein associated with neurodegenerative diseases

FDA advisory panel recommends reintroduction of Lotronex for irritable bowel syndrome

Celltech and Biogen collaborate on CDP-571

Immunosuppressants and their application described by Merck

European filing for Erbitux in colorectal and head and neck cancers delayed until 2003

New treatments for IBD in early development at Nobex

Lilly designs series of glutamate receptor function enhancers

Takeda presents novel somatostatin receptor antagonists useful for diabetes and related disorders

Peptidomimetic HCV protease inhibitors under study at Lilly

Alpha1B-adrenoceptor antagonists for the treatment of urinary tract disorders

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