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BioWorld Science

May 7, 2002

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Inhale Therapeutic Systems extends research collaboration with Johnson & Johnson

PK-11195 may be effective in improving clinical outcomes in acute myeloid leukemia

In vivo protection against ischemia-induced apoptosis in the brain by KR-31378

A new class of PDE4 inhibitors shows potential for the treatment of inflammatory lung diseases

Improvement of learning impairment obtained with Otsuka's sigma/5-HT1A receptor agonist

Efficacy of long-term DPP-IV inhibition in the treatment of diabetes confirmed in rat studies

Anecortave stabilizes or improves vision in AMD according to preliminary phase II results

Long-acting prophylactic efficacy demonstrated for ISV-401 in rabbit keratitis model

VEGF antagonist distinguishes between pathological and appropriate retinal revascularization

Tick-derived histamine-binding protein effective in murine model of allergic conjunctivitis

Complete pain relief obtained in hemicrania continua patients with high-dose COX-2 inhibitors

Donepezil improves cognition in patients with vascular dementia

Ribozyme reveals clinical program progress

First-quarter 2002 highlights offered by Icos

IL-13-PE38 granted fast track designation for malignant glioma

New Telik compounds have the ability to enhance insulin-dependent glucose uptake

ISTA acquires rights to late-stage ophthalmology products

Immtech and Neurochem enter agreement for antiamyloid compounds

1-Arylpiperazines claimed by Merck KGaA for use in schizophrenia

Merck Frosst synthesizes dipeptide inhibitors of caspase 3

BioVisioN and Novo Nordisk evaluate new therapeutic approaches to type 2 diabetes

Antitumor activity reported by SRI for benzopyran-based enzyme inhibitors

Merck presents newest inhibitors of farnesyl- and geranylgeranyltransferases

Potent and selective mu opioid agonists with analgesic activity

Farnesoid X receptor modulators identified at Tularik

Protonix delayed-release tablets approved for long-term treatment of Zollinger-Ellison syndrome

Bioption and IAVI partner on AIDS vaccines

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