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BioWorld Science

June 10, 2002

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Integrin antagonists in early development at Bayer

Neuropeptide Y ligands identified at Servier

Novel reverse transcriptase inhibitors presented by Roche

Bicyclic heterocycles for pain and other uses

Pierre Fabre presents new protein prenyltransferase inhibitors

Antimicrobial erythromycins identified at Hokuriku Seiyaku

Coenzyme A-peptide conjugates for use in cancer

Irofulven plus Xeloda evaluated in phase I trial in advanced solid tumors

Angiostatin-AAV reduces tumor burden and increases survival in preclinical trials

CAI resistance proteins available for licensing from NIH

Methods for enhanced distribution of therapeutic agents after local delivery available from NIH

Calpain inhibition may limit cardiac ischemia-reperfusion damage

Liposome encapsulation of known anticancer drugs improves tolerance, pharmacokinetics

Clinically significant P-gp inhibition obtained in AML patients with zosuquidar

Lofexidine is safe and attenuates withdrawal signs during opiate detoxification

Oncolytic adenovirus construct for intratumoral delivery characterized at ASGT meeting

Broad-spectrum antitumor activity demonstrated for telomerase promoter-driven therapeutic virus

MLN-341 and MLN-581 granted fast track designation

Potential therapeutic benefit of inhibitors of the MAPK pathway in lung diseases

Zambon licenses Vectura's PowderHale technology for dry powder inhaler product

TH-9507 improves immune function in the elderly

Esteve invests in HemispheRx

FDA approves Ritalin LA for ADHD

Oxford BioMedica adds Repoxygen for anemia to development portfolio

American Biogenetic Sciences seeks partners for oral smallpox vaccine

Domantis receives E.U. grant for domain antibody research

Omapatrilat superior to enalapril in patients with systolic hypertension

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